Antiretroviral therapy restores the homeostatic state of microglia in SIVâinfected rhesus macaques
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0422-635r
Abstract: Microglia and macrophages are essential for homeostatic maintenance and innate immune response in the brain. They are the first line of defense against infections such as HIV/SIV in the brain. However, they are susceptible to… read more here.
Keywords: state; antiretroviral therapy; brain; state microglia ... See more keywords
Interleukin-33 regulates the functional state of microglia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1012968
Abstract: Microglia, the most prominent resident immune cells, exhibit multiple functional states beyond their immunomodulatory roles. Non-immune functions such as synaptic reorganization, removal of cellular debris, and deposition of abnormal substances are mediated by phagocytosis of… read more here.
Keywords: regulates functional; functional state; interleukin regulates; state microglia ... See more keywords