Stathmin 1 Is Highly Expressed in Acute Promyelocytic Leukemia and Microtubule Dynamics Is a Potential Target for ATRA-Resistant APL Cells
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.2514.2514
Abstract: Introduction : Stathmin 1 is a microtubule destabilizer protein involved in the proliferation and differentiation of early hematopoietic progenitors. Aberrant Stathmin 1 expression has been reported in hematological malignancies. Stathmin 1 silencing reduces cell proliferation… read more here.
Keywords: microtubule; test; acute promyelocytic; pml rar ... See more keywords
Relationship of low stathmin expression and benefit from TPF induction chemotherapy and its role in chemoresistance via mutant p53 in oral cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e18034
Abstract: e18034Background: A phase 3 trial (NCT01542931) demonstrated failure to improve survival when docetaxel, cisplatin, and 5-fluorouracil (TPF) based induction chemotherapy was added to standard thera... read more here.
Keywords: stathmin expression; relationship low; induction; induction chemotherapy ... See more keywords
Decrease in stathmin expression by arsenic trioxide inhibits the proliferation and invasion of osteosarcoma cells via the MAPK signal pathway
Sign Up to like & getrecommendations! Published in 2017 at "Oncology Letters"
DOI: 10.3892/ol.2017.6347
Abstract: Osteosarcoma (OS) is the most common type of malignant bone tumor in children and adolescents. In total, 40–50% of patients with OS experience metastasis, and thus have a poor prognosis. Our previous study demonstrated that… read more here.
Keywords: arsenic trioxide; invasion; expression; mg63 dox ... See more keywords