Cost-effectiveness of Contemporary Statin Use Guidelines With or Without Coronary Artery Calcium Assessment in African American Individuals.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.1240
Abstract: Importance Clinical and economic consequences of statin treatment guidelines supplemented by targeted coronary artery calcium (CAC) assessment have not been evaluated in African American individuals, who are at increased risk for atherosclerotic cardiovascular disease and… read more here.
Keywords: statin; acc aha; cac assessment; american individuals ... See more keywords
Perioperative Statin Use in Noncardiac Surgery: Who and When?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2016.8037
Abstract: Postoperative morbidity and mortality account for billions of dollars in health care expenditure and millions of additional patient days in the hospital.1 Use of hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) in the perioperative period… read more here.
Keywords: statin use; surgery; statin; intensity ... See more keywords
Statin-Associated Myopathy-An Elusive Clinical Problem.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2018.3128
Abstract: Muscle disorders resulting from statin therapy, the most common manifestation of statin intolerance, are vexing to both patients and physicians. Statin-associated myopathy may appear as a spectrum of manifestations that include myalgias, myopathy, myositis, myonecrosis,… read more here.
Keywords: medicine; statin associated; statin; associated myopathy ... See more keywords
Assessment of omega‐3 carboxylic acids in statin‐treated patients with high levels of triglycerides and low levels of high‐density lipoprotein cholesterol: Rationale and design of the STRENGTH trial
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cardiology"
DOI: 10.1002/clc.23055
Abstract: It is uncertain whether omega‐3 fatty acids are beneficial in statin‐treated patients. Epanova is a mix of omega‐3 free fatty acids, not requiring co‐ingestion with food, which can lower triglycerides by up to 31%. STRENGTH… read more here.
Keywords: strength; risk; trial; statin ... See more keywords
Inflammation, coronary plaque progression, and statin use: A secondary analysis of the Risk Stratification with Image Guidance of HMG CoA Reductase Inhibitor Therapy (RIGHT) study
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cardiology"
DOI: 10.1002/clc.23808
Abstract: Statin treatment is a potent lipid‐lowering therapy associated with decreased cardiovascular risk and mortality. Recent studies including the PARADIGM trial have demonstrated the impact of statins on promoting calcified coronary plaque. read more here.
Keywords: coronary plaque; therapy; statin; risk ... See more keywords
Statin intensity and risk for cardiovascular events after heart transplantation
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12784
Abstract: Statins improve survival and reduce rejection and cardiac allograft vasculopathy after heart transplantation (HT). The impact of different statin intensities on clinical outcomes has never been assessed. We set out to determine the impact of… read more here.
Keywords: statin intensity; heart; intensity risk; statin ... See more keywords
Step‐by‐step diagnosis and management of the nocebo/drucebo effect in statin‐associated muscle symptoms patients: a position paper from the International Lipid Expert Panel (ILEP)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12960
Abstract: Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with statin therapy [most commonly statin‐associated muscle symptoms (SAMS)] result in the discontinuation of therapy and consequently increase the risk of adverse cardiovascular outcomes.… read more here.
Keywords: nocebo drucebo; drucebo effect; muscle; statin ... See more keywords
High-throughput Screening for Prescribing Cascades among Real World Statin Initiators.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacoepidemiology and drug safety"
DOI: 10.1002/pds.5607
Abstract: Statins are among the most prevalent medications prescribed and associated with adverse events that may prompt additional treatment (i.e., a prescribing cascade). No comprehensive assessment of statin‐related prescribing cascades has been performed to our knowledge. read more here.
Keywords: cascades among; throughput screening; statin; high throughput ... See more keywords
Statin Persistence and Adherence among Older Initiators: A Nationwide Cohort Study Using the National Health Insurance Claims Database in Japan.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacoepidemiology and drug safety"
DOI: 10.1002/pds.5622
Abstract: PURPOSE This study clarifies the reality of persistence and adherence to statins in older Japanese people who initiated statin use and compares it between primary and secondary prevention cohorts. METHODS The nationwide study using the… read more here.
Keywords: persistence; adherence; prevention; statin ... See more keywords
The relationship between post-diagnostic statin usage and breast cancer prognosis varies by hormone receptor phenotype: a systemic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-021-06065-z
Abstract: Preclinical studies and epidemiologic data had indicated statins had antineoplastic properties in breast cancer patients. Since breast cancer treatment is based on its phenotype, it is important to explore influence of post-diagnosis statin usage on… read more here.
Keywords: hormone receptor; statin; breast cancer; post ... See more keywords
In response to letter to the editor “Statin use in patients undergoing carotid artery endarterectomy: still much to be uncovered”
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-019-03803-w
Abstract: To the editor: We thank Zheng et al. for their interest in our meta-analysis of perioperative and long-term outcomes in patients receiving statin therapy before carotid endarterectomy, and their comments regarding the profound academic importance… read more here.
Keywords: endarterectomy; heterogeneity; analysis; statin ... See more keywords