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Published in 2019 at "Journal of General Internal Medicine"
DOI: 10.1007/s11606-019-05180-7
Abstract: Robust evidence is lacking on optimal timing of statin administration and its impact on patient outcomes. This study aims to evaluate among incident statin users the relationship between those prescribed evening vs. daily dosing instructions,…
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Keywords:
evening daily;
dosing instructions;
incident statin;
statin ... See more keywords
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Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2018.101088
Abstract: Background While statins may have anti-inflammatory effects, anti-oxidative effects are controversial. We investigated if statin treatment is associated with differences in oxidatively generated nucleotide damage and chronic inflammation, and the relationship between nucleotide damage and…
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Keywords:
compared non;
inflammation;
statin;
non users ... See more keywords
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Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.05.160
Abstract: BACKGROUND Carotid artery endarterectomy (CEA) remains the most common surgical intervention for the treatment of symptomatic and asymptomatic carotid artery stenosis. Several studies have shown a lower risk of periprocedural adverse events in statin users…
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Keywords:
carotid artery;
statin patients;
statin users;
meta analysis ... See more keywords
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Published in 2020 at "Prostate Cancer and Prostatic Diseases"
DOI: 10.1038/s41391-020-0207-5
Abstract: Background Increasing evidence indicates an association between statins and reduced prostate cancer-specific mortality (PCSM). However, significant bias may exist in these studies. One particularly challenging bias to assess is the healthy user effect, which may…
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Keywords:
cancer;
statin users;
prostate cancer;
mortality ... See more keywords
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Published in 2021 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2021.02.019
Abstract: OBJECTIVE To investigate whether prior statin therapy is associated with an improvement in mortality among patients who undergo extracorporeal membrane oxygenation (ECMO) therapy. DESIGN Retrospective, population-based, cohort study. SETTING Health records were obtained from the…
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Keywords:
mortality;
statin therapy;
prior statin;
therapy ... See more keywords
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Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000023427
Abstract: Abstract Differences in the mechanism of action and potential pleiotropic effects between statins and fibrates would potentially drive a different effect on various laboratory parameters, but this remains controversial because of a paucity of reports…
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Keywords:
statin users;
statins fibrates;
fibrate users;
matched pairs ... See more keywords
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Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2016-210936
Abstract: Objectives To examine the association between the use of statins and the risk of systemic lupus erythematosus (SLE) with focus on describing the patterns of risks over time. Setting A population-based cohort study using the…
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Keywords:
based cohort;
systemic lupus;
population based;
lupus erythematosus ... See more keywords
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Published in 2021 at "Journal of the American Heart Association"
DOI: 10.1161/jaha.121.022330
Abstract: Background Small observational studies have suggested that statin users have a lower risk of dying with COVID-19. We tested this hypothesis in a large, population-based cohort of adults in 2 of Canada's most populous provinces:…
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Keywords:
population based;
statin;
sars cov;
cov infection ... See more keywords
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Published in 2017 at "Vascular"
DOI: 10.1177/1708538116684942
Abstract: Objectives Prior studies examining the effects of statins on arterial aneurysm development and progression yielded conflicting results due to their smaller size and presence of residual confounders. The objective of this study is to examine…
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Keywords:
aneurysm;
peripheral visceral;
visceral artery;
aortic peripheral ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.742273
Abstract: The coronavirus disease-2019 (COVID-19) is caused by SARS-CoV-2, leading to acute respiratory distress syndrome (ARDS), thrombotic complications, and myocardial injury. Statins, prescribed for lipid reduction, have anti-inflammatory, anti-thrombotic, and immunomodulatory properties and are associated with…
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Keywords:
covid patients;
statin users;
statin;
mortality ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.815882
Abstract: Background: For non-dialysis patients with hyperlipidemia, statins may provide clinical benefits in reducing mortality risk; however, the optimal treatment for dialysis patients with hyperlipidemia remains debatable. We evaluated the mortality risks for hyperlipidemic patients with…
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Keywords:
disease;
statin users;
statin therapy;
hyperlipidemic patients ... See more keywords