A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering
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DOI: 10.1002/pro.4425
Abstract: We challenged the stabilization of a G‐protein coupled receptor (GPCR) in the active state solely by multiple amino‐acid mutations without the agonist binding. For many GPCRs, the free energy of the active state is higher… read more here.
Keywords: statistical thermodynamics; state; methodology; active state ... See more keywords
Statistical thermodynamics of uniaxial ferroelectric: exactly solved model
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DOI: 10.1080/00150193.2019.1592448
Abstract: Abstract A detailed analysis of the thermodynamic properties of uniaxial ferroelectrics is carried out within the framework of an exactly soluble model with an infinite radius of interactions. The free energy of a ferroelectric in… read more here.
Keywords: energy; thermodynamics; within framework; statistical thermodynamics ... See more keywords
The Use of the Embedded-Atom Method in Statistical Thermodynamics of Metals
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DOI: 10.1134/s0031918x1807013x
Abstract: An expression for the Helmholtz energy of a metal has been derived using the embedded-atom method (EAM) within the classical perturbation theory. An expression for the effective three-particle distribution function with effective three-particle interactions taken… read more here.
Keywords: method statistical; embedded atom; use embedded; thermodynamics ... See more keywords