Articles with "stattic analogues" as a keyword



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STAT3 inhibitor Stattic and its analogues inhibit STAT3 phosphorylation and modulate cytokine secretion in senescent tumour cells

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Published in 2023 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2023.12968

Abstract: Signal transducer and activator of transcription 3 (STAT3) signalling serves an important role in carcinogenesis and cellular senescence, and its inhibition in tumour cells represents an attractive therapeutic target. Premature cellular senescence, a process of… read more here.

Keywords: stattic analogues; tumour cells; stat3; senescence ... See more keywords