Prediction of Long-term Survival After Status Epilepticus Using the ACD Score.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.0609
Abstract: Importance Early prediction of long-term mortality in status epilepticus is important given the high fatality rate in the years after diagnosis. Objective To improve prognostication of long-term mortality after status epilepticus diagnosis. Design, Settings, and… read more here.
Keywords: status; long term; acd score; status epilepticus ... See more keywords
Intranasal midazolam as first‐line inhospital treatment for status epilepticus: a pharmaco‐EEG cohort study
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50932
Abstract: We sought to evaluate the efficacy and tolerability of intranasal midazolam (in‐MDZ) as first‐line inhospital therapy in patients with status epilepticus (SE) during continuous EEG recording. read more here.
Keywords: first line; line inhospital; intranasal midazolam; status epilepticus ... See more keywords
Successful management of super‐refractory status epilepticus with thalamic deep brain stimulation
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24821
Abstract: Super‐refractory status epilepticus is a condition characterized by recurrence of status epilepticus despite use of deep general anesthesia, and it has high morbidity and mortality rates. We report a case of a 17‐year‐old boy with… read more here.
Keywords: status; refractory status; deep brain; stimulation ... See more keywords
Brexanolone as adjunctive therapy in super‐refractory status epilepticus
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.25008
Abstract: Super‐refractory status epilepticus (SRSE) is a life‐threatening form of status epilepticus that continues or recurs despite 24 hours or more of anesthetic treatment. We conducted a multicenter, phase 1/2 study in SRSE patients to evaluate… read more here.
Keywords: status; brexanolone adjunctive; refractory status; status epilepticus ... See more keywords
Treatment of early life status epilepticus: What can we learn from animal models?
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia Open"
DOI: 10.1002/epi4.12271
Abstract: Treatment of status epilepticus (SE) in infants and children is challenging. There is a recognition that a broad set of developmental processes need to be considered to fully appreciate the physiologic complexity of severe seizures,… read more here.
Keywords: status epilepticus; treatment; life; severe seizures ... See more keywords
Estimating the period prevalence of non‐convulsive status epilepticus among comatose adults at the University Teaching Hospital in Lusaka, Zambia
Sign Up to like & getrecommendations! Published in 2019 at "Epilepsia Open"
DOI: 10.1002/epi4.12358
Abstract: In Western settings, non‐convulsive status epilepticus (NCSE) and non‐convulsive seizures (NCSz) are associated with high mortality. In comatose patients, interictal epileptiform discharges (IEDs) identified on routine electroencephalogram (EEG) are predictive of NCSE/NCS. Little is known… read more here.
Keywords: convulsive status; non convulsive; prevalence; status epilepticus ... See more keywords
The outcome of early life status epilepticus—lessons from laboratory animals
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12664
Abstract: Status epilepticus (SE) is the most common neurologic emergency in children. Both clinical and laboratory studies have demonstrated that SE in early life can cause brain damage and permanent behavioral abnormalities, trigger epileptogenesis, and interfere… read more here.
Keywords: laboratory; early life; status epilepticus;
Reactive oxygen species in status epilepticus
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DOI: 10.1002/epi4.12691
Abstract: It has long been recognized that status epilepticus can cause considerable neuronal damage, and this has become one of its defining features. The mechanisms underlying this damage are less clear. Excessive activation of NMDA receptors… read more here.
Keywords: reactive oxygen; status epilepticus; oxygen species; species status ... See more keywords
Sex‐based structural and functional MRI outcomes in the rat brain after soman (GD) exposure‐induced status epilepticus
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia Open"
DOI: 10.1002/epi4.12701
Abstract: Exposure to the nerve agent, soman (GD), induces status epilepticus (SE), epileptogenesis, and even death. Although rodent models studying the pathophysiological mechanisms show females to be more reactive to soman, no tangible sex differences in… read more here.
Keywords: status epilepticus; sex based; sex; soman ... See more keywords
In the fast lane: Receptor trafficking during status epilepticus
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia Open"
DOI: 10.1002/epi4.12718
Abstract: Status epilepticus (SE) remains a significant cause of morbidity and mortality and often is refractory to standard first‐line treatments. A rapid loss of synaptic inhibition and development of pharmacoresistance to benzodiazepines (BZDs) occurs early during… read more here.
Keywords: receptor trafficking; receptor; ampa; status epilepticus ... See more keywords
Introduction to the special issue on status epilepticus: neuronal injury, plasticity, and therapies; Celebrating the legacy of Dr. Claude G. Wasterlain
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DOI: 10.1002/epi4.12724
Abstract: We are delighted to present this Special Issue of Epilepsia Open as a tribute to Dr. Claude G. Wasterlain, his many years of service and immense contributions to clinical and basic epileptology. We open this… read more here.
Keywords: claude wasterlain; special issue; claude; status epilepticus ... See more keywords