Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization† †This work is dedicated to Prof. Ron Raines on the occasion of his 60th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc01345h
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DOI: 10.1039/c9sc01345h
Abstract: Vinylphosphonites react in chemoselective Staudinger-phosphonite reactions (SPhR) with azides to form vinylphosphonamidates for the subsequent modification of cysteine residues in peptides and proteins. read more here.
Keywords: staudinger induced; vinylphosphonites staudinger; induced chemoselective; peptide cyclization ... See more keywords