Efficacy of primary liver organoid culture from different stages of non-alcoholic steatohepatitis (NASH) mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119823
Abstract: Non-alcoholic steatohepatitis (NASH) is associated with liver fibrosis and cirrhosis, which eventually leads to hepatocellular carcinoma. Although several animal models were developed to understand the mechanisms of NASH pathogenesis and progression, it remains obscure. A… read more here.
Keywords: non alcoholic; alcoholic steatohepatitis; liver; steatohepatitis nash ... See more keywords
Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis (NASH).
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20211122
Abstract: Annexin A1 (AnxA1) is an important effector in the resolution of inflammation which is involved in modulating hepatic inflammation in nonalcoholic steatohepatitis (NASH). In this study we have investigated the possible effects of treatment with… read more here.
Keywords: steatohepatitis nash; inflammation; annexin; treatment ... See more keywords
Targeting CCR2/5 in the treatment of nonalcoholic steatohepatitis (NASH) and fibrosis: opportunities and challenges
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2020.1718106
Abstract: In parallel to the obesity pandemic, nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in adults worldwide [1]. Especially its inflammatory form, nonalcoholic steatohepatitis (NASH), but ‘simple steatosis’… read more here.
Keywords: fibrosis; nonalcoholic steatohepatitis; liver; steatohepatitis nash ... See more keywords
A diabetologist’s perspective of non‐alcoholic steatohepatitis (NASH): Knowledge gaps and future directions
Sign Up to like & getrecommendations! Published in 2020 at "Liver International"
DOI: 10.1111/liv.14350
Abstract: There is a close link between steatohepatitis (NASH) and Type 2 diabetes (T2DM). Recently, the American Diabetes Association (ADA) recommended screening for NASH and advanced fibrosis in patients with diabetes and hepatic steatosis or elevated… read more here.
Keywords: future directions; steatohepatitis nash; knowledge gaps; nash ... See more keywords
A new method to induce nonalcoholic steatohepatitis (NASH) in mice
Sign Up to like & getrecommendations! Published in 2019 at "BMC Gastroenterology"
DOI: 10.1186/s12876-019-1041-x
Abstract: BackgroundGeneral overnutrition is one of the key factors involved in the development of nonalcoholic fatty liver disease (NAFLD) as the most common liver disease occur by two steps of liver injury ranges from steatosis to… read more here.
Keywords: nonalcoholic steatohepatitis; new method; liver; steatohepatitis nash ... See more keywords
Hepatocellular carcinoma in the context of non-alcoholic steatohepatitis (NASH): recent advances in the pathogenic mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "Hormone Molecular Biology and Clinical Investigation"
DOI: 10.1515/hmbci-2019-0044
Abstract: Abstract Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is particularly aggressive and is one of the leading causes of cancer mortality. In recent decades, the epidemiological landscape of HCC has… read more here.
Keywords: hepatocellular carcinoma; non alcoholic; pathogenic mechanisms; alcoholic steatohepatitis ... See more keywords
Nonalcoholic Steatohepatitis (NASH) and Atherosclerosis: Explaining Their Pathophysiology, Association and the Role of Incretin-Based Drugs
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11061060
Abstract: Nonalcoholic steatohepatitis (NASH) is the most severe manifestation of nonalcoholic fatty liver disease (NAFLD), a common complication of type 2 diabetes, and may lead to cirrhosis and hepatocellular carcinoma. Oxidative stress and liver cell damage… read more here.
Keywords: incretin based; steatohepatitis nash; nash atherosclerosis; atherosclerosis ... See more keywords
Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21239021
Abstract: Nonalcoholic steatohepatitis (NASH) is characterized by hepatic steatosis with inflammation and fibrosis. Membrane endoglin (Eng) expression is shown to participate in fibrosis, and plasma concentrations of soluble endoglin (sEng) are increased in patients with hypercholesterolemia… read more here.
Keywords: nonalcoholic steatohepatitis; cholesterol; steatohepatitis nash; seng ... See more keywords
Non-Alcoholic Steatohepatitis (NASH) and Organokines: What Is Now and What Will Be in the Future
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010498
Abstract: Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, lobular inflammation, and enlargement of the diameter of hepatocytes (ballooning hepatocytes), with or without fibrosis. It affects 20% of patients with non-alcoholic fatty liver disease (NAFLD). Due to… read more here.
Keywords: steatohepatitis nash; non alcoholic; alcoholic steatohepatitis; nash organokines ... See more keywords
Exosomal microRNAs and Progression of Nonalcoholic Steatohepatitis (NASH)
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113501
Abstract: Nonalcoholic fatty liver disease (NAFLD)/metabolic associated fatty liver disease (MAFLD) is becoming a public health problem worldwide. Steatosis as the simple form and nonalcoholic steatohepatitis (NASH) as its progression form are commonly seen in liver… read more here.
Keywords: steatohepatitis nash; progression; nonalcoholic steatohepatitis; nash exosomal ... See more keywords