Artemlavanins A and B from Artemisia lavandulaefolia and Their Cytotoxicity Against Hepatic Stellate Cell Line LX2
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DOI: 10.1007/s13659-020-00254-0
Abstract: Two new sesquiterpenoids, artemlavanins A (1) and B (3), together with fifteen known compounds (2 and 4−17) were isolated from the EtOH extract of Artemisia lavandulaefolia. The structures of new compounds were elucidated by extensive… read more here.
Keywords: stellate cell; cytotoxicity hepatic; artemisia lavandulaefolia; lx2 ... See more keywords
Alogliptin alleviates liver fibrosis via suppression of activated hepatic stellate cell.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.02.065
Abstract: Liver fibrosis occurs in most types of chronic liver diseases. The understanding of the pathogenesis of liver fibrosis has grown considerably, but the effective treatments are still lacking. Alogliptin, a classical Dipeptidyl peptidase-4 (DPP4) inhibitor… read more here.
Keywords: stellate cell; fibrosis; liver fibrosis; alogliptin ... See more keywords
Commentary on “Re‐regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β‐catenin signaling via interaction with Gli1”
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DOI: 10.1111/bph.15282
Abstract: Correspondence Ralf Weiskirchen, Institute of Molecular Pathobiochemistry, Experimental GeneTherapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D52074 Aachen, Germany. Email: [email protected] Funding information Deutsche Forschungsgemeinschaft (SFB/TRR57), Grant/Award Numbers: P13, Q3; Interdisciplinary Centre for Clinical… read more here.
Keywords: contraction cirrhotic; stellate cell; commentary regulation; cell contraction ... See more keywords
A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell
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DOI: 10.1155/2018/7361684
Abstract: Background Our previous studies have shown that islet stellate cell (ISC), similar to pancreatic stellate cell (PSC) in phenotype and biological characters, may be responsible for the islet fibrosis in type 2 diabetes. To further… read more here.
Keywords: stellate cell; pancreatic stellate; islet stellate; analysis ... See more keywords
Abstract 5148: Secreted ccdc80 from hepatic stellate cell promote invasion and epithelial-mesenchymal transition in hepatocellular carcinoma
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DOI: 10.1158/1538-7445.am2018-5148
Abstract: Liver cirrhosis is the most important risk factor for hepatocellular carcinoma (HCC) and hepatic stellate cell (HSC) has pivotal role in developing cirrhosis by producing various extracellular matrix (ECM). HSC are essential mediators of tumor… read more here.
Keywords: stellate cell; invasion; ccdc80; expression ... See more keywords
Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
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DOI: 10.1371/journal.pone.0274219
Abstract: Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC… read more here.
Keywords: cell; cell line; stellate cell; immortalized hepatic ... See more keywords
Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis
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DOI: 10.3350/cmh.2020.0037
Abstract: Cytoglobin (Cygb), a stellate cell-specific globin, has recently drawn attention due to its association with liver fibrosis. In the livers of both humans and rodents, Cygb is expressed only in stellate cells and can be… read more here.
Keywords: stellate cell; fibrosis; role; hepatic fibrosis ... See more keywords
Hepatic Stellate Cell: A Double-Edged Sword in the Liver.
Sign Up to like & getrecommendations! Published in 2021 at "Physiological research"
DOI: 10.33549/physiolres.934755
Abstract: Hepatic stellate cells (HSCs) are located in the space of Disse, between liver sinusoidal endothelia cells (LSECs) and hepatocytes. They have surprised and excited hepatologists for their biological characteristics. Under physiological quiescent conditions, HSCs are… read more here.
Keywords: liver fibrosis; hepatic stellate; liver; stellate cell ... See more keywords
Role of Metabolism in Hepatic Stellate Cell Activation and Fibrogenesis
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DOI: 10.3389/fcell.2018.00150
Abstract: Activation of hepatic stellate cell (HSC) involves the transition from a quiescent to a proliferative, migratory, and fibrogenic phenotype (i.e., myofibroblast), which is characteristic of liver fibrogenesis. Multiple cellular and molecular signals which contribute to… read more here.
Keywords: stellate cell; fibrogenesis; hepatic stellate; activation ... See more keywords
Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.976549
Abstract: Stellate cells are principal neurons in the entorhinal cortex that contribute to spatial processing. They also play a role in the context of Alzheimer’s disease as they accumulate Amyloid beta early in the disease. Producing… read more here.
Keywords: stellate cells; cell; role; forward programming ... See more keywords
Hepatic Stellate Cell-Immune Interactions in NASH
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.867940
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the dominant cause of liver disease worldwide. Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is characterized by severe hepatocellular injury, inflammation, and fibrosis. Chronic inflammation and heightened… read more here.
Keywords: cell; cell immune; stellate cell; immune interactions ... See more keywords