Pathogenetic Characteristics of Mesenchymal Stem Cells in Hidradenitis Suppurativa
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.2516
Abstract: Importance Hidradenitis suppurativa (HS) is a disease of the terminal hair follicle in apocrine gland–enriched skin areas, where immunobiology dysregulation of mesenchymal stem cells (MSCs) may have a key role. Objective To investigate the MSC… read more here.
Keywords: iqr; median iqr; healthy controls; stem cells ... See more keywords
Glycans in stem cell regulation: from Drosophila tissue stem cells to mammalian pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13167
Abstract: Cell surface glycans, which are tissue‐specific and developmentally regulated, work as essential modulators in ligand–receptor interactions, binding to various signal ligands including Wnt, Hedgehog, fibroblast growth factors, epidermal growth factors, and bone morphogenetic proteins, as… read more here.
Keywords: tissue stem; stem cell; drosophila tissue; stem ... See more keywords
Revealing the metabolic characteristics of human embryonic stem cells by genome‐scale metabolic modeling
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13255
Abstract: Embryonic stem cells (ESCs) are characterized by a dual capacity, self‐renewal and pluripotency, which can be regulated by metabolism. A better understanding of ESC metabolism and regulatory mechanisms is pivotal for research into development, ageing,… read more here.
Keywords: genome scale; metabolic characteristics; embryonic stem; stem ... See more keywords
The paradox of metabolism in quiescent stem cells
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13608
Abstract: The shift between a proliferating and a nonproliferating state is associated with significant changes in metabolic needs. Proliferating cells tend to have higher metabolic rates, and their metabolic profiles facilitate biosynthesis, as compared to those… read more here.
Keywords: metabolic profiles; paradox metabolism; stem; stem cells ... See more keywords
Fine‐tuning Nanog expression heterogeneity in embryonic stem cells by regulating a Nanog transcript‐specific microRNA
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13936
Abstract: In embryonic stem cells (ESCs), the transcription factor Nanog maintains the stemness of ESCs despite exhibiting heterogeneous expression patterns under varied culture conditions. Efficient fine‐tuning of Nanog expression heterogeneity could enable ESC proliferation and differentiation… read more here.
Keywords: stem cells; expression; embryonic stem; expression heterogeneity ... See more keywords
Glioblastoma stem cells express non‐canonical proteins and exclusive mesenchymal‐like or non‐mesenchymal‐like protein signatures
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13355
Abstract: Glioblastoma’s (GBM) origin, recurrence and resistance to treatment are driven by GBM cancer stem cells (GSCs). Existing transcriptomic characterisations of GBM classify the tumours to three subtypes: classical, proneural, and mesenchymal. The comprehension of how… read more here.
Keywords: non mesenchymal; mesenchymal like; like protein; gscs ... See more keywords
The mitochondrial fission factor FIS1 promotes stemness of human lung cancer stem cells via mitophagy
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13207
Abstract: Mitophagy, a form of autophagy, plays a role in cancer development, progression and recurrence. Cancer stem cells (CSCs) also play a key role in these processes, although it not known whether mitophagy can regulate the… read more here.
Keywords: cancer stem; mitochondrial fission; cancer; fis1 ... See more keywords
Expansion Microscopy‐based imaging for visualization of mitochondria in Drosophila ovarian germline stem cells
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13506
Abstract: Recent studies have shown that mitochondrial morphology can modulate organelle function and greatly affect stem cell behavior, thus affecting tissue homeostasis. As such, we previously showed that the accumulation of fragmented mitochondria in aged Drosophila… read more here.
Keywords: drosophila ovarian; microscopy; ovarian germline; germline stem ... See more keywords
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13538
Abstract: Feeder cells play an important role in the culture of human pluripotent stem cells (hPSCs) in vitro. Previously, we used methanol as a fixative to prepare feeder cells for the cultivation of pluripotent stem cells (PSCs),… read more here.
Keywords: pluripotent stem; self renewal; feeder cells; cells treated ... See more keywords
Spontaneous Differentiation of Human Neural Stem Cells on Nanodiamonds
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800299
Abstract: The potential use of stem cells in regenerative medicine requires the ability to be able to control stem cell fate as cellular networks are developed. Here, nanodiamonds (≈10 nm) are supported on glass and shown… read more here.
Keywords: spontaneous differentiation; human neural; stem; stem cells ... See more keywords
Efficient Single‐Dose Induction of Osteogenic Differentiation of Stem Cells Using Multi‐Bioactive Hybrid Nanocarriers
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.202000123
Abstract: Bone regeneration requires the presence of specific factors to induce the differentiation of stem cells into osteoblasts. These factors induce osteogenesis by stimulating the expression of bone‐related proteins, bone cell proliferation and differentiation. Herein, bioactive… read more here.
Keywords: stem cells; differentiation; differentiation stem; osteogenic differentiation ... See more keywords