Isolation, Culture, and Differentiation of Mammary Epithelial Stem/Progenitor Cells from Fresh or Ex Vivo Cultured Human Breast Tissue
Sign Up to like & getrecommendations! Published in 2019 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.65
Abstract: In vivo transplantation is the gold standard method for characterization of stem/progenitor cell self‐renewal, tissue regeneration, and tumorigenesis. The method requires an enriched population of stem cells that represent a small fraction of a given… read more here.
Keywords: progenitor cells; tissue; stem progenitor; stem ... See more keywords
Bone marrow as a target and accomplice of vascular complications in diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3240
Abstract: Peripheral vascular complications are common in diabetic patients. While pathogenic mechanisms have received much consideration, only recently regenerative processes captured attention. There is now a consensus that the bone marrow is a source of reparative… read more here.
Keywords: progenitor cells; bone; stem progenitor; vascular complications ... See more keywords
Transcriptome analysis of the response to thyroid hormone in Xenopus neural stem and progenitor cells
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.535
Abstract: The thyroid hormones—thyroxine (T4) and 3,5,3′triiodothyronine (T3)—regulate the development of the central nervous system (CNS) in vertebrates by acting in different cell types. Although several T3 target genes have been identified in the brain, the… read more here.
Keywords: neural stem; progenitor cells; response; stem progenitor ... See more keywords
Safety, feasibility and effectiveness of first in‐human administration of muscle‐derived stem/progenitor cells modified with connexin‐43 gene for treatment of advanced chronic heart failure
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.700
Abstract: To assess the safety and efficacy of transendocardial delivery of muscle‐derived stem/progenitor cells with connexin‐43 overexpression (Cx‐43‐MDS/PC) in advanced heart failure (HF). read more here.
Keywords: heart; muscle derived; heart failure; derived stem ... See more keywords
Skeletal Stem/Progenitor Cells in Periosteum and Skeletal Muscle Share a Common Molecular Response to Bone Injury
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4616
Abstract: Bone regeneration involves skeletal stem/progenitor cells (SSPCs) recruited from bone marrow, periosteum, and adjacent skeletal muscle. To achieve bone reconstitution after injury, a coordinated cellular and molecular response is required from these cell populations. Here,… read more here.
Keywords: bone; stem progenitor; skeletal muscle; periosteum skeletal ... See more keywords
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α‐actinin4 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28379
Abstract: Neural stem/progenitor cells (NSPCs) are a promising candidate for the cell‐replacement therapy after central nervous system (CNS) injury. However, the short of sufficient NSPCs migration and integration into the lesions is an essential challenge for… read more here.
Keywords: migration; stem progenitor; cspg; nspcs migration ... See more keywords
E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29457
Abstract: Leukemia stem cells (LSCs) have critical functions in acute leukemia (AL) pathogenesis, participating in its initiation and relapse. Thus, identifying new molecules to eradicate LSCs represents a high priority for AL management. This work identified… read more here.
Keywords: progenitor cells; acute leukemia; stem progenitor; stem ... See more keywords
Novel differential calcium regulation of hematopoietic stem and progenitor cells under physiological low oxygen conditions.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30942
Abstract: Low oxygen bone marrow (BM) niches (~1%-4% low O2 ) provide critical signals for hematopoietic stem/progenitor cells (HSC/HSPCs). Our presented data are the first to investigate live, sorted HSC/HSPCs in their native low O2 conditions.… read more here.
Keywords: low oxygen; stem progenitor; hematopoietic stem; regulation ... See more keywords
mTOR signaling plays a critical role in the defects observed in muscle‐derived stem/progenitor cells isolated from a murine model of accelerated aging
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23409
Abstract: Mice expressing reduced levels of ERCC1‐XPF (Ercc1−/Δ mice) demonstrate premature onset of age‐related changes due to decreased repair of DNA damage. Muscle‐derived stem/progenitor cells (MDSPCs) isolated from Ercc1−/Δ mice have an impaired capacity for cell… read more here.
Keywords: muscle derived; mtor signaling; derived stem; stem progenitor ... See more keywords
The gp130 Cytokine Interleukin‐11 Regulates Engraftment of Vav1–/– Hematopoietic Stem and Progenitor Cells in Lethally Irradiated Recipients
Sign Up to like & getrecommendations! Published in 2018 at "STEM CELLS"
DOI: 10.1002/stem.2760
Abstract: During bone marrow transplantation, hematopoietic stem and progenitor cells (HSPCs) respond to signals from the hematopoietic microenvironment by coordinately activating molecular pathways through Rho GTPases, including Rac. We have previously shown that deletion of Vav1,… read more here.
Keywords: irradiated recipients; stem progenitor; hematopoietic stem; hspcs ... See more keywords
A Nestin–Cyclin‐Dependent Kinase 5–Dynamin‐Related Protein 1 Axis Regulates Neural Stem/Progenitor Cell Stemness via a Metabolic Shift
Sign Up to like & getrecommendations! Published in 2018 at "STEM CELLS"
DOI: 10.1002/stem.2769
Abstract: Neural stem/progenitor cells (NSPCs) transplantation provides an alternative approach for various central nervous system (CNS) diseases treatment, while the difficulties in NSPC acquisition and expansion limit their further application. Unveiling the mechanism of NSPC stemness… read more here.
Keywords: stem progenitor; related protein; stem; dynamin related ... See more keywords