Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells
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DOI: 10.1002/advs.202503897
Abstract: Glioblastoma (GBM) is the most malignant primary brain tumor in adults, with glioma stem cells (GSCs) as a subpopulation contributing to treatment resistance and recurrence. This study investigates the role of lactate and its regulatory… read more here.
Keywords: vrk1; stem; stemness proliferation; gscs ... See more keywords
The SW480 cell line, overexpressing PIWIL2 gene, maintains the expression of stemness and proliferation genes in the mice xenografts
Sign Up to like & getrecommendations! Published in 2023 at "Gastroenterology and Hepatology From Bed to Bench"
DOI: 10.22037/ghfbb.v16i1.2661
Abstract: Aim: This study aims to confirm previous fundamental in vitro findings about the PIWIL2 gene by investigating the effects of its overexpression on cell cycle, proliferation, apoptosis, and stem cell expression markers in colorectal cancer… read more here.
Keywords: cell; proliferation; cell line; expression ... See more keywords