One step access to oxindole-based β-lactams through Ugi four-center three-component reaction
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DOI: 10.1039/c8ra08165d
Abstract: A multicomponent Ugi reaction involving isatin, isocyanide and β-amino acid components has been developed. The reactions proceeded smoothly to give β-lactam-containing 3,3-disubstituted oxindoles in only one step and generally high yields. When chiral, non racemic,… read more here.
Keywords: oxindole based; step access; access oxindole; one step ... See more keywords