Articles with "step dosing" as a keyword



Panel Interview of ONcology practices with Emergent Experience of teclistamab in the Real world: the TecPIONEER Study

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Published in 2024 at "Current Medical Research and Opinion"

DOI: 10.1080/03007995.2024.2352856

Abstract: Abstract Objective To understand clinicians’ current teclistamab step-up dosing (SUD) model and how they envision future administration models, as well as perceived barriers and facilitators to these models in day-to-day clinical practice. Methods Interviews of… read more here.

Keywords: oncology; step dosing; multiple myeloma; treatment ... See more keywords

Phase I Study of Safety, Tolerability, and Efficacy of Tebentafusp Using a Step-Up Dosing Regimen and Expansion in Patients With Metastatic Uveal Melanoma

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Published in 2022 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.21.01805

Abstract: PURPOSE This phase I study aimed to define the recommended phase II dose (RP2D) of tebentafusp, a first-in-class T-cell receptor/anti-CD3 bispecific protein, using a three-week step-up dosing regimen, and to assess its safety, pharmacokinetics, pharmacodynamics,… read more here.

Keywords: phase; dosing regimen; efficacy; phase study ... See more keywords