A practical and step-economic route to Favipiravir
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DOI: 10.1007/s11696-017-0208-6
Abstract: A practical and step-economic route to Favipiravir, an antiviral drug, was developed. Favipiravir was synthesized in only six steps from 3-aminopyrazine-2-carboxylic acid with an overall yield of about 22.3%. Key intermediates 3 and 6 were… read more here.
Keywords: economic route; step; practical step; step economic ... See more keywords
Atom- and step-economic synthesis of π-conjugated large oligomers via C H activated oligomerization
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DOI: 10.1016/j.dyepig.2018.10.075
Abstract: Abstract A new synthetic concept for π-conjugated oligomers has been developed by simply tuning the molar ratio between two co-monomers to switch the standard polymerization to one-step oligomerization. Three diketopyrrolopyrrole (DPP)-based conjugated oligomers sequentially consisting… read more here.
Keywords: conjugated oligomers; atom step; activated oligomerization; step economic ... See more keywords
Atom- and step-economic 1,3-thiosulfonylation of activated allenes with thiosulfonates to access vinyl sulfones/sulfides.
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DOI: 10.1039/d2cc01731h
Abstract: A new type of organocatalyzed 1,3-thiosulfonylation has been developed to straightforwardly access highly functionalized vinyl sulfones, which features mild conditions, atom- and step-economy, practicability, conciseness, and environmental friendliness. Moreover, these valuable products can be transformed… read more here.
Keywords: atom step; step economic; vinyl sulfones; thiosulfonylation ... See more keywords