Comparison of linezolid step-down therapy to standard parenteral therapy in methicillin-resistant Staphylococcus aureus bloodstream infections.
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DOI: 10.1016/j.ijantimicag.2021.106329
Abstract: OBJECTIVE Data supporting oral step-down therapy in methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections (BSI) are sparse; linezolid offers potential in this setting. The study objective was to determine the effectiveness and safety of oral step-down… read more here.
Keywords: step therapy; therapy methicillin; step; resistant staphylococcus ... See more keywords
Efficacy of sequential three-step empirical therapy for chronic cough
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DOI: 10.1177/1753465817711187
Abstract: Background: Empirical three-step therapy has been proved in just one hospital. This study aimed to demonstrate applicability of the sequential empirical three-step therapy for chronic cough in different clinical settings. Methods: Sequential empirical three-step therapy… read more here.
Keywords: three step; step therapy; secondary care; step ... See more keywords
Variation In Use And Content Of Prescription Drug Step Therapy Protocols, Within And Across Health Plans.
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DOI: 10.1377/hlthaff.2021.00822
Abstract: Insurers limit the use of certain prescription drugs by requiring step therapy-that is, by allowing access only after alternatives have been tried and have failed. Using data from seventeen of the largest US commercial health… read more here.
Keywords: health plans; step therapy; step; therapy protocols ... See more keywords
Risk Factors for Asthma Exacerbation and Treatment Failure in Adults and Adolescents with Well‐controlled Asthma during Continuation and Step‐Down Therapy
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DOI: 10.1513/annalsats.201711-886oc
Abstract: Rationale: Although national and international guidelines recommend reduction of asthma controller therapy or “step‐down” therapy in patients with well‐controlled asthma, it is expected that some individuals may experience worsening of asthma symptoms or asthma exacerbations… read more here.
Keywords: step therapy; treatment; risk; treatment failure ... See more keywords
Physician Perceptions of Step Therapy Prescribing Requirements.
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DOI: 10.18553/jmcp.2019.25.11.1210
Abstract: BACKGROUND Step therapy policies that require prescribers to follow an ordered protocol for drug choices are widely used by public and private insurers to manage medication costs; however, the perceptions of prescribing physicians regarding these… read more here.
Keywords: medicine; step therapy; endocrinology; therapy policies ... See more keywords
Real-world utilization of top-down and step-up therapy and initial costs in Crohn disease.
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DOI: 10.18553/jmcp.2022.28.8.849
Abstract: BACKGROUND: Medication treatment strategies for Crohn disease (CD) include step-up (SU) therapy, beginning with oral anti-inflammatory agents, and top-down (TD) therapy, beginning with biologics or immunomodulators. The real-world utilization and short-term medical costs associated with… read more here.
Keywords: medication; therapy; crohn disease; step therapy ... See more keywords