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   Articles with "stepped wedge" as a keyword



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Novel methods for the analysis of stepped wedge cluster randomized trials.

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recommendations! Published in 2019 at "Statistics in medicine"

DOI: 10.1002/sim.8451

Abstract: Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes, often chosen for their feasibility advantages. SW-CRTs must account for time trends in the outcome… read more here.

Keywords: analysis; cluster randomized; stepped wedge; wedge cluster ... See more keywords
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Information content of stepped wedge designs with unequal cluster-period sizes in linear mixed models: Informing incomplete designs.

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recommendations! Published in 2021 at "Statistics in medicine"

DOI: 10.1002/sim.8867

Abstract: In practice, stepped wedge trials frequently include clusters of differing sizes. However, investigations into the theoretical aspects of stepped wedge designs have, until recently, typically assumed equal numbers of subjects in each cluster and in… read more here.

Keywords: information; incomplete designs; wedge; cluster period ... See more keywords
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Power analysis for stepped wedge trials with multiple interventions

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recommendations! Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9301

Abstract: Stepped wedge design (SWD) trials are cluster randomized trials that feature staggered, unidirectional cross‐over between treatment conditions. Existing literature on power for SWDs focuses primarily on designs with two conditions, typically a control and an… read more here.

Keywords: wedge trials; analysis stepped; power; stepped wedge ... See more keywords
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Model misspecification in stepped wedge trials: Random effects for time or treatment

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recommendations! Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9326

Abstract: Mixed models are commonly used to analyze stepped wedge trials (SWTs) to account for clustering and repeated measures on clusters. One critical issue researchers face is whether to include a random time effect or a… read more here.

Keywords: wedge trials; stepped wedge; effect; treatment ... See more keywords
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The batched stepped wedge design: A design robust to delays in cluster recruitment

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recommendations! Published in 2022 at "Statistics in Medicine"

DOI: 10.1002/sim.9438

Abstract: Stepped wedge designs are an increasingly popular variant of longitudinal cluster randomized trial designs, and roll out interventions across clusters in a randomized, but step‐wise fashion. In the standard stepped wedge design, assumptions regarding the… read more here.

Keywords: wedge; wedge designs; stepped wedge; batched stepped ... See more keywords
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Acute coronary syndrome quality improvement in Kerala (ACS QUIK): Rationale and design for a cluster‐randomized stepped‐wedge trial

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recommendations! Published in 2017 at "American Heart Journal"

DOI: 10.1016/j.ahj.2016.10.026

Abstract: &NA; Ischemic heart disease is the leading cause of death in India, and there are likely more myocardial infarctions in India than in any other country in the world. We have previously reported heterogeneous care… read more here.

Keywords: quality; quality improvement; cluster randomized; randomized stepped ... See more keywords
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Variations in stepped-wedge cluster randomized trial design: Insights from the Patient-Centered Care Transitions in Heart Failure trial.

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recommendations! Published in 2019 at "American heart journal"

DOI: 10.1016/j.ahj.2019.08.017

Abstract: The stepped-wedge (SW) cluster randomized controlled trial, in which clusters cross over in a randomized sequence from control to intervention, is ideal for the implementation and testing of complex health service interventions. In certain cases… read more here.

Keywords: trial; heart; stepped wedge; wedge cluster ... See more keywords
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swCRTdesign: An RPackage for Stepped Wedge Trial Design and Analysis

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recommendations! Published in 2020 at "Computer methods and programs in biomedicine"

DOI: 10.1016/j.cmpb.2020.105514

Abstract: BACKGROUND AND OBJECTIVE Stepped wedge trials (SWTs) are a type of cluster-randomized trial that are commonly used to evaluate health care interventions. Most SWT-related software packages have restrictive assumptions about the study design and correlation… read more here.

Keywords: design analysis; correlation; trial design; stepped wedge ... See more keywords
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Proposed variations of the stepped-wedge design can be used to accommodate multiple interventions.

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recommendations! Published in 2017 at "Journal of clinical epidemiology"

DOI: 10.1016/j.jclinepi.2017.04.004

Abstract: OBJECTIVES Stepped-wedge design (SWD) cluster-randomized trials have traditionally been used for evaluating a single intervention. We aimed to explore design variants suitable for evaluating multiple interventions in an SWD trial. STUDY DESIGN AND SETTING We… read more here.

Keywords: intervention; wedge design; multiple interventions; stepped wedge ... See more keywords
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Key concepts in clinical epidemiology: Stepped wedge trials.

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recommendations! Published in 2021 at "Journal of clinical epidemiology"

DOI: 10.1016/j.jclinepi.2021.04.003

Abstract: A stepped wedge trial evaluates an intervention that is implemented over a number of time periods according to a staggered timetable. Stepped wedge trials are usually cluster randomised, the intervention being delivered at some geographical,… read more here.

Keywords: intervention; wedge trials; clinical epidemiology; epidemiology ... See more keywords
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A maximum likelihood approach to power calculations for stepped wedge designs of binary outcomes.

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recommendations! Published in 2018 at "Biostatistics"

DOI: 10.1093/biostatistics/kxy031

Abstract: In stepped wedge designs (SWD), clusters are randomized to the time period during which new patients will receive the intervention under study in a sequential rollout over time. By the study's end, patients at all… read more here.

Keywords: binary outcomes; power; approach; stepped wedge ... See more keywords