Exploiting Carvone To Demonstrate Both Stereocontrol and Regiocontrol: 1,2- vs 1,4-Addition of Grignard Reagents and Organocuprates
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DOI: 10.1021/acs.jchemed.7b00892
Abstract: The ability of certain organometallic reagents to react via 1,2- or 1,4-addition to an α,β-unsaturated ketone is a fundamental example of regioselectivity at the second-year undergraduate organic level. The following two experiments were designed to… read more here.
Keywords: addition; exploiting carvone; demonstrate stereocontrol; stereocontrol regiocontrol ... See more keywords