Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters
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DOI: 10.1021/jacs.2c03192
Abstract: Bastimolide B is a polyhydroxy macrolide isolated from marine cyanobacteria displaying antimalarial activity. It features a dense array of hydroxylated stereogenic centers with 1,5-relationships along a hydrocarbon chain. These 1,5-polyols represent a particularly challenging motif… read more here.
Keywords: synthesis bastimolide; synthesis; bastimolide using; stereocontrolled total ... See more keywords
The Stereocontrolled Total Synthesis of Polyketide Natural Products: A Thirty-Year Journey
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DOI: 10.1246/bcsj.20200309
Abstract: The diverse and complex structures of polyketide natural products have stimulated the imagination of synthetic chemists for decades. Captivated by their often impressive biological activities and t... read more here.
Keywords: products thirty; natural products; polyketide natural; total synthesis ... See more keywords