Stereodefined synthesis of the four possible stereoisomers of 5,18-diHETE
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DOI: 10.1016/j.tet.2018.01.053
Abstract: Abstract Because of the structural similarity between 5,18-diHETE and anti-inflammatory resolvin E2, synthesis of 5,18-diHETE was studied. Methyl (R)-3-hydroxyvalerate was converted to the (R)-C9–C20 phosphonium salt via alkylation of the derived iodide with propargyl alcohol… read more here.
Keywords: possible stereoisomers; synthesis four; four possible; stereodefined synthesis ... See more keywords