Construction of Axial Chirality and Silicon-Stereogenic Center via Rh-Catalyzed Asymmetric Ring-Opening of Silafluorenes.
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DOI: 10.1021/acs.orglett.1c00935
Abstract: A rhodium-catalyzed enantioselective ring-opening/acylation of silafluorenes is reported. The newly developed bulky phosphoramidite ligand, in combination with methanol as the additive, enabled the reaction to create one axial chirality and one silicon-stereogenic center in a… read more here.
Keywords: axial chirality; ring opening; stereogenic center; silicon stereogenic ... See more keywords