Strategies to synthesize a chiral helical polymer accompanying with two stereogenic centers for chiral electroanalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2022.339810
Abstract: In most cases, the recognition efficiency of chiral electroanalysis relies on the chiral carbon center, whereas its medium is just used to transfer the electron. Differently, in this study, an ionic helical polymer with right-… read more here.
Keywords: chiral electroanalysis; polymer; helical polymer; stereogenic centers ... See more keywords
Catalytic Enantio- and Diastereoselective Cyclopropanation of 2-Azadienes for the Synthesis of Aminocyclopropanes Bearing Quaternary Carbon Stereogenic Centers.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02692
Abstract: We report the catalytic enantio- and diastereoselective preparation of aminocyclopropanes by the cyclopropanation of terminal and (Z)-internal 2-azadienes with donor/acceptor carbenes derived from α-diazoesters. The resulting cyclopropanes bear quaternary carbon stereogenic centers vicinal to the… read more here.
Keywords: enantio diastereoselective; carbon; quaternary carbon; carbon stereogenic ... See more keywords
A convergent fragment coupling strategy to access quaternary stereogenic centers
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc07023e
Abstract: The formation of quaternary stereogenic centers via convergent fragment coupling is a longstanding challenge in organic synthesis. Here, we report a strategy for the formation of quaternary stereogenic centers in polycyclic systems based upon the… read more here.
Keywords: convergent fragment; stereogenic centers; coupling strategy; quaternary stereogenic ... See more keywords
H-Bond Mediated Phase-Transfer Catalysis: Enantioselective Generating of Quaternary Stereogenic Centers in β-Keto Esters
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27082508
Abstract: In this work, we would like to present the development of a highly optimized method for generating the quaternary stereogenic centers in β-keto esters. This enantioselective phase-transfer alkylation catalyzed by hybrid Cinchona catalysts allows for… read more here.
Keywords: phase transfer; generating quaternary; quaternary stereogenic; stereogenic centers ... See more keywords
Desymmetrization of Cyclic 1,3-Diketones under N-Heterocyclic Carbene Organocatalysis: Access to Organofluorines with Multiple Stereogenic Centers
Sign Up to like & getrecommendations! Published in 2021 at "Research"
DOI: 10.34133/2021/9867915
Abstract: Symmetric 1,3-diketones with fluorine or fluorinated substituents on the prochiral carbon remain to be established. Herein, we have developed a novel prochiral fluorinated oxindanyl 1,3-diketone and successfully applied these substrates in carbene-catalyzed asymmetric desymmetrization. Accordingly,… read more here.
Keywords: desymmetrization cyclic; cyclic diketones; diketones heterocyclic; multiple stereogenic ... See more keywords