Regio- and Stereoselective N-addition to an Open Bromo Vinyl Cation
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153173
Abstract: Abstract A protocol for the synthesis of thus far inaccessible bromo vinyl triflimides is presented. Our previously reported concept of assisted vinyl cation formation was engaged to achieve both a protonation of relatively electron poor… read more here.
Keywords: cation; vinyl cation; stereoselective addition; bromo vinyl ... See more keywords
Regio- and Stereoselective Addition to gem-Difluorinated Ene-Ynamides: Access to Stereodefined Fluorinated Dienes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01593
Abstract: The first synthesis of gem-difluorinated ene-ynamides is presented via deprotonation of trifluoromethylated N-allenamides and δ extrusion of fluorine. These highly reactive building blocks, owing to their dual functional groups, offer a unique entry to difluorinated… read more here.
Keywords: addition; gem difluorinated; ene ynamides; difluorinated ene ... See more keywords
Recyclable Pd(OAc) 2 /2P(3-tol) 3 /PEG-400 System for Regio- and Stereoselective Addition of Boronic Acids to Ynamides
Sign Up to like & getrecommendations! Published in 2024 at "Synthesis"
DOI: 10.1055/s-0043-1775404
Abstract: Pd(OAc) 2 /2P(3-tol) 3 in poly(ethylene glycol) (PEG-400) is shown to be a highly efficient catalyst for the regio- and stereoselective addition of boronic acids to ynamides. The reaction proceeds smoothly at 70 °C with… read more here.
Keywords: peg 400; regio stereoselective; stereoselective addition; oac tol ... See more keywords