Highly Stereoselective Asymmetric Total Synthesis of (-)-Jimenezin via Sequential Intramolecular Amide Enolate Alkylation.
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DOI: 10.1021/acs.orglett.2c00196
Abstract: A highly stereoselective asymmetric total synthesis of (-)-jimenezin (1), a potent anticancer acetogenin, was efficiently completed with the key feature being a sequential intramolecular amide enolate alkylation (IAEA). Our investigation to probe the origin of… read more here.
Keywords: highly stereoselective; sequential intramolecular; stereoselective asymmetric; total synthesis ... See more keywords