Highly stereoselective and enantiodivergent synthesis of cyclopropylphosphonates with engineered carbene transferases
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DOI: 10.1039/d2sc01965e
Abstract: Organophosphonate compounds have represented a rich source of biologically active compounds, including enzyme inhibitors, antibiotics, and antimalarial agents. Here, we report the development of a highly stereoselective strategy for olefin cyclopropanation in the presence of… read more here.
Keywords: enantiodivergent synthesis; stereoselective enantiodivergent; carbene; highly stereoselective ... See more keywords