Total Synthesis of Immunosuppressive Mycestericin E and G Enabled by a Highly Stereoselective Nitroso-Ene Cyclization.
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DOI: 10.1021/acs.orglett.3c01082
Abstract: This report describes a streamlined synthesis of immunosuppressive mycestericin E and G through a highly stereoselective nitroso-ene cyclization in 11-12 steps using readily available materials. The stereochemical outcome in the formation of a Nα-quaternary stereogenic… read more here.
Keywords: synthesis immunosuppressive; stereoselective nitroso; nitroso ene; highly stereoselective ... See more keywords