Dynamic Kinetic Resolution-Enabled Highly Stereoselective Nucleophilic Fluoroalkylation to Access Chiral β-Fluoro Amines.
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DOI: 10.1021/acs.orglett.2c02250
Abstract: β-Fluorinated amine is highly desirable for biological and pharmaceutical science, because replacing a C-H bond with a C-F bond can change the physical and chemical properties of the parent molecule to a large extent but… read more here.
Keywords: highly stereoselective; stereoselective nucleophilic; chiral fluoro; dynamic kinetic ... See more keywords