Stereospecific Synthesis of Phosphatidylglycerol Using a Cyanoethyl Phosphoramidite Precursor.
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2020.104933
Abstract: Phosphatidylglycerols (PG) are a family of naturally occurring phospholipids that are responsible for critical operations within cells. PG are characterized by an (R) configuration in the diacyl glycerol backbone and an (S) configuration in the… read more here.
Keywords: phosphoramidite precursor; stereospecific synthesis; synthesis phosphatidylglycerol; phosphatidylglycerol using ... See more keywords
Regio- and stereospecific synthesis of dl-4,5-dibromo-4,5-dideoxy-3,6-O-methyl-chiro-inositol
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.02.050
Abstract: Abstract The regio- and stereospecific synthesis of dl -4,5-dibromo-4,5-dideoxy-3,6-O-methyl-chiro-inositol is reported. Bromination of p-benzoquinone followed by reduction of the carbonyl groups with NaBH4 gave the corresponding trans-dibromodiol compound, which was reacted with sodium methoxide to… read more here.
Keywords: stereospecific synthesis; dibromo dideoxy; synthesis dibromo; dideoxy methyl ... See more keywords
Stereospecific synthesis of 1,5-disubstituted tetrazoles from ketoximes via a Beckmann rearrangement facilitated by diphenyl phosphorazidate
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DOI: 10.1016/j.tetlet.2019.04.014
Abstract: Abstract A novel method for the stereospecific synthesis of 1,5-disubstituted tetrazoles from ketoximes via the Beckmann rearrangement was developed using diphenyl phosphorazidate (DPPA) as both the oxime activator and azide source. Various ketoximes were transformed… read more here.
Keywords: tetrazoles ketoximes; disubstituted tetrazoles; stereospecific synthesis; synthesis disubstituted ... See more keywords
Boron-Promoted Umpolung Reaction of Sulfonyl Chlorides for the Stereospecific Synthesis of Thioglycosides via Reductive Deoxygenation Coupling Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00353
Abstract: S-Glycosides have broad biological activities and serve as stable mimics of natural O-glycoside counterparts and thus are of great therapeutic potential. Herein we disclose an efficient method for the stereospecific synthesis of 1-thioglycosides via a… read more here.
Keywords: boron promoted; reductive deoxygenation; thioglycosides via; deoxygenation coupling ... See more keywords
Stereospecific Synthesis of the Saccharosamine-Rhamnose-Fucose Fragment Present in Saccharomicin B.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b02028
Abstract: A synthetic route has been developed for constructing the d-saccharosamine-l-rhamnose-d-fucose (Sac-Rha-Fuc) trisaccharide fragment present in the antibacterial natural product saccharomicin B. The Sac monosaccharide was synthesized through a modified nine step procedure starting from d-rhamnal… read more here.
Keywords: stereospecific synthesis; rhamnose fucose; fragment present; saccharosamine rhamnose ... See more keywords
Expedient iron-catalyzed stereospecific synthesis of triazines via cycloaddition of aziridines with diaziridines.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc10089j
Abstract: Iron-catalyzed stereospecific [3+3]-annulation of aziridines with diaziridines is described to furnish [1,2,4]-triazines in high yield at room temperature. The use of an inexpensive iron salt catalyst, substrate scope and enantiomeric purity are the important practical… read more here.
Keywords: stereospecific synthesis; expedient iron; iron catalyzed; catalyzed stereospecific ... See more keywords
Stereospecific synthesis of S-(-)-trans-verbenol and its antipode by inversion of sterically hindered alcohols.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2020.1839433
Abstract: S-(-)-trans-Verbenol (1) and its antipode, R-(+)-trans-verbenol (1') have been confirmed as the critical pheromone components of bark beetles. Synthesis of these two active secondary alcohols (1 and 1') from commercially available starting materials S-α-pinene and… read more here.
Keywords: hindered alcohols; inversion; stereospecific synthesis; sterically hindered ... See more keywords