Copper-Catalyzed Stereospecific Transformations of Alkylboronic Esters.
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DOI: 10.1021/jacs.2c04037
Abstract: Copper-catalyzed stereospecific cross-couplings of boronic esters are reported. Boron "ate" complexes derived from pinacol boronic esters and tert-butyl lithium undergo stereospecific transmetalation to copper cyanide, followed by coupling with alkynyl bromides, allyl halides, propargylic halides,… read more here.
Keywords: transformations alkylboronic; catalyzed stereospecific; stereospecific transformations; alkylboronic esters ... See more keywords
Stereospecific Transformations of Alkylboronic Esters Enabled by Direct Boron-to-Zinc Transmetalation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c01677
Abstract: Chiral secondary organoboronic esters, when activated with t-butyllithium, are shown to undergo efficient stereoretentive transmetalation with either zinc acetate or zinc chloride. This reaction provides chiral secondary alkylzinc reagents that are configurationally stable under practical… read more here.
Keywords: transformations alkylboronic; stereospecific transformations; zinc; transmetalation ... See more keywords