Sterically controlled mechanochemistry under hydrostatic pressure
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DOI: 10.1038/nature25765
Abstract: Mechanical stimuli can modify the energy landscape of chemical reactions and enable reaction pathways, offering a synthetic strategy that complements conventional chemistry. These mechanochemical mechanisms have been studied extensively in one-dimensional polymers under tensile stress… read more here.
Keywords: sterically controlled; mechanochemistry hydrostatic; controlled mechanochemistry; hydrostatic pressure ... See more keywords
Sterically controlled isodesmic late-stage C–H iodination of arenes
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DOI: 10.1039/d3sc00801k
Abstract: Aryl iodides are key motifs in organic chemistry due to their versatility as linchpins in metal-mediated cross-coupling reactions for synthesis and drug discovery. These scaffolds are typically prepared indirectly from prefunctionalized starting materials or via… read more here.
Keywords: iodination arenes; sterically controlled; late stage; iodination ... See more keywords