Rational Engineered C-Acyltransferase Transforms Sterically Demanding Acyl Donors
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04617
Abstract: The biocatalytic Friedel–Crafts acylation has been identified recently for the acetylation of resorcinol using activated acetic acid esters for the synthesis of acetophenone derivatives catalyzed by an acyltransferase. Because the wild-type enzyme is limited to… read more here.
Keywords: engineered acyltransferase; transforms sterically; rational engineered; acyltransferase transforms ... See more keywords
Formation of silaimines from a sterically demanding iminophosphonamido chlorosilylene via intramolecular N-P bond cleavage.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc02812j
Abstract: The sterically demanding iminophosphonamido chlorosilylene [Ph2P(DipN)2]SiCl (Dip = 2,6-diisopropylphenyl) was synthesized and fully characterized using NMR spectroscopy and X-ray crystallography. Substitution reactions of [Ph2P(DipN)2]SiCl with N- and Fe-nucleophiles led to the unexpected formation of the… read more here.
Keywords: intramolecular bond; sterically demanding; via intramolecular; demanding iminophosphonamido ... See more keywords
A synthetic tactic to substitute axial ligands in sterically demanding Ru(II)porphyrinates.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt01095j
Abstract: We report a synthetic strategy that allows for the preparation of sterically encumbered heteroleptic Ru(II)porphyrinates with the desired configuration of stable/inert and weak/labile axial ligands to direct reactions between substrates to exclusively occur at the… read more here.
Keywords: tactic substitute; substitute axial; axial ligands; sterically demanding ... See more keywords