ROS–NLRP3 signaling pathway induces sterile inflammation after thulium laser resection of the prostate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30663
Abstract: The sterile inflammation (SI) of the urinary tract is a common problem requiring serious consideration after prostatectomy. This study mainly focuses on the role of the reactive oxygen species–NLR family, pyrin domain‐containing 3 (ROS–NLRP3) signaling… read more here.
Keywords: ros nlrp3; sterile inflammation; signaling pathway; nlrp3 signaling ... See more keywords
Sterile inflammation in thoracic transplantation
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03615-7
Abstract: The life-saving benefits of organ transplantation can be thwarted by allograft dysfunction due to both infectious and sterile inflammation post-surgery. Sterile inflammation can occur after necrotic cell death due to the release of endogenous ligands… read more here.
Keywords: thoracic transplantation; inflammation; sterile inflammation; inflammation thoracic ... See more keywords
DAMPs and sterile inflammation in drug hepatotoxicity
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology International"
DOI: 10.1007/s12072-018-9911-9
Abstract: Drug hepatotoxicity is the leading cause of acute liver failure (ALF) in the developed countries. The early diagnosis and treatment are still problematic, and one important reason is the lack of reliable mechanistic biomarkers and… read more here.
Keywords: phase; drug hepatotoxicity; acetaminophen; sterile inflammation ... See more keywords
NOX2 NADPH oxidase controls responses to infection and sterile inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.092
Abstract: The NOX2 NADPH oxidase generates superoxide following activation by microbial or other inflammatory stimuli. Inactivating mutations in this leukocyte enzyme result in chronic granulomatous disease (CGD), a primary immunodeficiency associated with recurrent bacterial and fungal… read more here.
Keywords: oxidase; nox2 nadph; sterile inflammation; nadph oxidase ... See more keywords
Inhibition of snake venom induced sterile inflammation and PLA2 activity by Titanium dioxide Nanoparticles in experimental animals
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47557-y
Abstract: Sterile inflammation (SI) is an essential process in response to snakebite and injury. The venom induced pathophysiological response to sterile inflammation results into many harmful and deleterious effects that ultimately leads to death. The available… read more here.
Keywords: venom; titanium dioxide; venom induced; sterile inflammation ... See more keywords
HMGB1 is a mediator of cuproptosis-related sterile inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.996307
Abstract: Cuproptosis is a recently recognized modality of cell death driven by intracellular copper-dependent mitochondrial stress. However, the mediators of the sterile inflammatory response to cuproptotic death are undetermined. Here, we report that high-mobility group box… read more here.
Keywords: mediator cuproptosis; cuproptosis; hmgb1; sterile inflammation ... See more keywords
Etiological Value of Sterile Inflammation in Preeclampsia: Is It a Non-Infectious Pregnancy Complication?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.694298
Abstract: Understanding of sterile inflammation and its associated biological triggers and diseases is still at the elementary stage. This becomes more warranted in cases where infections are not associated with the pathology. Detrimental effects of bacterial… read more here.
Keywords: pregnancy; value sterile; inflammation; etiological value ... See more keywords
Link between sterile inflammation and cardiovascular diseases: Focus on cGAS-STING pathway in the pathogenesis and therapeutic prospect
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.965726
Abstract: Sterile inflammation characterized by unresolved chronic inflammation is well established to promote the progression of multiple autoimmune diseases, metabolic disorders, neurodegenerative diseases, and cardiovascular diseases, collectively termed as sterile inflammatory diseases. In recent years, substantial… read more here.
Keywords: sting pathway; cardiovascular diseases; sterile inflammation; cgas sting ... See more keywords
Gut-Derived Sterile Inflammation and Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.831090
Abstract: The etiology of Parkinson's disease (PD) is unknown, but evidence is increasing that there is a prominent inflammatory component to the illness. Epidemiological, genetic, and preclinical evidence support a role for gut-derived sterile inflammation. Pro-inflammatory… read more here.
Keywords: inflammation; parkinson disease; evidence; sterile inflammation ... See more keywords
Loss of the Sympathetic Signal Produces Sterile Inflammation of the Prostate
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.855376
Abstract: Neural innervations exert essential roles in the prostate. However, spatial distribution and regulatory function of such neural inputs are incompletely characterized. Here, we exploited the advanced whole-tissue immunolabeling and optical clearing technique to assess the… read more here.
Keywords: inflammation; prostate; sympathetic signal; loss ... See more keywords
Necroptosis in Solid Organ Transplantation: A Literature Overview
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073677
Abstract: Ischemia-reperfusion injury (IRI) is encountered in various stages during solid organ transplantation (SOT). IRI is known to be a multifactorial inflammatory condition involving hypoxia, metabolic stress, leukocyte extravasation, cellular death (including apoptosis, necrosis and necroptosis)… read more here.
Keywords: organ transplantation; necroptosis; sterile inflammation; necroptosis solid ... See more keywords