Cost analysis on the use of rituximab and calcineurin inhibitors in children and adolescents with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s00467-017-3789-y
Abstract: BackgroundRituximab (RTX) is increasingly being used in place of calcineurin inhibitors (CNI) in pediatric patients with steroid-dependent nephrotic syndrome (SDNS). However, despite its favorable safety profile, its unit cost is prohibitive. We therefore compared the… read more here.
Keywords: calcineurin inhibitors; group; dependent nephrotic; steroid dependent ... See more keywords
Treatment strategies for children with steroid-dependent nephrotic syndrome: in need of controlled studies
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DOI: 10.1007/s00467-018-4012-5
Abstract: Sir, In their letter to the Editor [1], Fujinaga and Sakuraya briefly report details of their single-center experience with steroidsparing agents for the treatment of steroid-dependent nephrotic syndrome (SDNS) in children [2]. The variety of… read more here.
Keywords: treatment; dependent nephrotic; steroid dependent; frns sdns ... See more keywords
Randomized controlled trial on immunomodulatory effects of azithromycin in children with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s00467-019-04251-5
Abstract: BackgroundAzithromycin (AZM) is a macrolide antibiotic with anti-inflammatory and immunomodulatory effects. Our aim was to compare the immunomodulatory effects of AZM combined with steroid therapy with that of steroid therapy alone in children with steroid-dependent… read more here.
Keywords: children steroid; group; dependent nephrotic; immunomodulatory effects ... See more keywords
Immunoglobulin serum levels in rituximab-treated patients with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s00467-019-04398-1
Abstract: Background Rituximab (RTX) is efficient in steroid-dependent nephrotic syndrome (SDNS) in pediatric and adult patients. The aim of this study is to describe hypogammaglobulinemia as a side effect of RTX treatment. Methods All pediatric patients… read more here.
Keywords: nephrology; age; steroid dependent; rtx ... See more keywords
Assessment of factors associated with mizoribine responsiveness in children with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s10157-019-01754-1
Abstract: BackgroundSeveral immunosuppressants have been used to treat children with steroid-dependent nephrotic syndrome (SDNS). Mizoribine (MZR) is an immunosuppressant used to maintain remission in children with SDNS, although its effectiveness for treating SDNS remains controversial. Therefore,… read more here.
Keywords: children steroid; mzr; dependent nephrotic; steroid dependent ... See more keywords
Mycophenolate sodium for children with frequently relapsing or steroid dependent nephrotic syndrome
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DOI: 10.1007/s13312-017-1156-5
Abstract: In this retrospective study, patients with idiopathic frequentlyrelapsing nephrotic syndrome (FRNS) (n=27) and steroid dependent nephrotic syndrome (SDNS) (n=13) who received enteric coated mycophenolate sodium (ECMS) for at least 6 months, were included for analysis.… read more here.
Keywords: mycophenolate sodium; dependent nephrotic; steroid dependent; syndrome ... See more keywords
[Rituximab treatment in pediatric patients with steroid-dependent nephrotic syndrome: a tertiary hospital].
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DOI: 10.1016/j.anpedi.2020.12.010
Abstract: BACKGROUND Corticosteroids have had a central role in the treatment of nephrotic syndrome. The management of these patients who become dependent to steroids is complex, involving different immunosuppressive drugs patterns. The monoclonal antibody anti CD20,… read more here.
Keywords: rituximab; treatment; dependent nephrotic; steroid dependent ... See more keywords
Low dose IL-2 in patients with steroid-dependent dysimmune manifestations associated with myelodysplastic syndromes: a three-case report.
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DOI: 10.1093/rheumatology/keaa696
Abstract: OBJECTIVES Systemic inflammatory and autoimmune diseases can be associated with myelodysplastic syndromes. Current treatments (steroids, immunosuppressive agents, biologics) are unsatisfactory because of their low response rate, dependence or adverse events. We aimed at evaluating the… read more here.
Keywords: myelodysplastic syndromes; low dose; patients steroid; steroid dependent ... See more keywords
Clinical efficacy of mycophenolate mofetil versus levamisole therapy in frequently relapsing and steroid dependent childhood nephrotic syndrome – A retrospective comparative analysis
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DOI: 10.1111/nep.14067
Abstract: Children with frequently relapsing (FR) or steroid dependent (SD) nephrotic syndrome (NS) often develop side effects of corticosteroids. Various steroid‐sparing agents are in practice, but only a few studies exist so far which have compared… read more here.
Keywords: frequently relapsing; efficacy; relapsing steroid; steroid dependent ... See more keywords
G227 Rituximab in, frequently relapsing/steroid dependent nephrotic syndrome: does the dose matter?
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DOI: 10.1136/archdischild-2019-rcpch.222
Abstract: Background Rituximab (RTX) is a commonly used and effective treatment in frequently relapsing/steroid-dependent nephrotic syndrome (FR/SDNS) in children. Data regarding the most effective dosing regimen are however limited. Methods We conducted a multi-center retrospective cohort… read more here.
Keywords: frequently relapsing; dependent nephrotic; steroid dependent; rtx ... See more keywords
Minimal change disease with maximum immunosuppression: successful treatment of steroid-dependent minimal change disease with rituximab
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DOI: 10.1136/bcr-2017-223407
Abstract: Minimal change disease (MCD) is usually steroid sensitive, although in case of steroid dependent and multiple relapses we can struggle with different immunosuppressive agents, sometimes with no response. Rituximab has been emerging as an alternative… read more here.
Keywords: rituximab; change disease; minimal change; steroid dependent ... See more keywords