Multidimensional Separations of Intact Phase II Steroid Metabolites Utilizing LC-Ion Mobility-HRMS.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02163
Abstract: The detection and unambiguous identification of anabolic-androgenic steroid metabolites are essential in clinical, forensic, and antidoping analyses. Recently, sulfate phase II steroid metabolites have received increased attention in steroid metabolism and drug testing. In large… read more here.
Keywords: mass; steroid; ion mobility; phase steroid ... See more keywords
Delivery prediction by quantitative analysis of four steroid metabolites with liquid chromatography tandem mass spectrometry in asymptomatic pregnant women.
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DOI: 10.1080/07853890.2022.2067895
Abstract: BACKGROUND Prediction of delivery is important for assessing due dates, providing adequate prenatal care, and suggesting appropriate interventions in preterm and post-term pregnancies. Recent metabolomic findings suggested that the temporal abundance information of metabolome can… read more here.
Keywords: pregnant women; steroid metabolites; delivery prediction; prediction ... See more keywords
Ketoconazole- and Metyrapone-Induced Reductions on Urinary Steroid Metabolites Alter the Urinary Free Cortisol Immunoassay Reliability in Cushing Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.833644
Abstract: Introduction Twenty-four-hour urinary free cortisol (24h-UFC) is the most used test for follow-up decision-making in patients with Cushing syndrome (CS) under medical treatment. However, 24h-UFC determinations by immunoassays (IA) are commonly overestimated because of steroid… read more here.
Keywords: steroid metabolites; 24h ufc; urinary steroid; mtp ... See more keywords
Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts
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DOI: 10.3390/metabo12111108
Abstract: Recurrent respiratory infections are a leading cause of morbidity and mortality in early life, but there is no broadly accepted means to identify infection-prone children during this highly vulnerable period. In this study, we investigated… read more here.
Keywords: respiratory infections; infection; identify infection; steroid metabolites ... See more keywords
Online In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry for Automated Analysis of Four Sulfated Steroid Metabolites in Saliva Samples
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DOI: 10.3390/molecules27103225
Abstract: Accurate measurement of sulfated steroid metabolite concentrations can not only enable the elucidation of the mechanisms regulating steroid metabolism, but also lead to the diagnosis of various related diseases. The present study describes a simple… read more here.
Keywords: sulfated steroid; tube solid; metabolites saliva; saliva samples ... See more keywords