Steroid nuclear receptor coactivator 2 controls immune tolerance by promoting induced Treg differentiation via up-regulating Nr4a2
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DOI: 10.1126/sciadv.abn7662
Abstract: Steroid nuclear receptor coactivator 2 (SRC2) is a member of a family of transcription coactivators. While SRC1 inhibits the differentiation of regulatory T cells (Tregs) critical for establishing immune tolerance, we show here that SRC2… read more here.
Keywords: immune tolerance; nuclear receptor; treg differentiation; differentiation ... See more keywords