Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes.
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DOI: 10.1021/acsmedchemlett.1c00604
Abstract: Reversing protein aggregation within cells may be an important tool to fight protein-misfolding disorders such as Alzheimer's, Parkinson's, and cardiovascular diseases. Here we report the design and synthesis of a family of steroid-quinoline hybrid compounds… read more here.
Keywords: aggregation; steroid quinoline; quinoline hybrids; protein aggregation ... See more keywords