Impacts of endocrine-disrupting chemicals on prostate function and cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental research"
DOI: 10.1016/j.envres.2021.112085
Abstract: Because of their historical mode of action, endocrine-disrupting chemicals (EDCs) are associated with sex-steroid receptors, namely the two estrogen receptors (ERα and ERβ) and the androgen receptor (AR). Broadly, EDCs can modulate sex-steroid receptor functions.… read more here.
Keywords: sex steroid; endocrine disrupting; steroid receptors; cancer ... See more keywords
Steroid receptor/coactivator binding inhibitors: An update
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110471
Abstract: The purpose of this review is to highlight recent developments in small molecules and peptides that block the binding of coactivators to steroid receptors. These coactivator binding inhibitors bind at the coregulator binding groove, also… read more here.
Keywords: receptor coactivator; binding inhibitors; steroid receptors; coactivator binding ... See more keywords
Steroid receptors and vertebrate evolution
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110526
Abstract: Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago. Results from sequence analyses of… read more here.
Keywords: receptor; 000 genes; evolution steroid; steroid receptors ... See more keywords
Corrigendum to “Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?” [Prog. Neuro-Psychopharmacol. Biol. Psychiatry 71 (2016) 210–222]
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2017.06.014
Abstract: Corrigendum to “Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?” [Prog. NeuroPsychopharmacol. Biol. Psychiatry 71 (2016) 210–222] Cynthia L. Betheaa,b,c,⁎, Yelena Belikova, Kenny Phu, Grace Mammarella… read more here.
Keywords: steroid receptors; reproductive steroid; corrigendum reproductive; receptors actions ... See more keywords
Genome-wide crosstalk between steroid receptors in breast and prostate cancers
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine-Related Cancer"
DOI: 10.1530/erc-21-0038
Abstract: Steroid receptors (SRs) constitute an important class of signal-dependent transcription factors (TFs). They regulate a variety of key biological processes and are crucial drug targets in many disease states. In particular, estrogen (ER) and androgen… read more here.
Keywords: steroid receptors; breast prostate; prostate; genome wide ... See more keywords
Steroid Receptor Signallings as Targets for Resveratrol Actions in Breast and Prostate Cancer
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20051087
Abstract: Extensive research over the past 25 years in hormone-dependent cancers, such as breast cancer and prostate cancer, has identified the molecular mechanisms driven by steroid receptors, elucidating the interplay between genomic and non-genomic steroid receptors… read more here.
Keywords: signallings targets; steroid receptors; receptor signallings; prostate cancer ... See more keywords
Kelulut Honey Regulates Sex Steroid Receptors in a Polycystic Ovary Syndrome Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314757
Abstract: Reproductive and metabolic anomalies in polycystic ovary syndrome (PCOS) have been associated with the dysregulation of sex steroid receptors. Kelulut honey (KH) has been shown to be beneficial in PCOS-induced rats by regulating folliculogenesis and… read more here.
Keywords: polycystic ovary; expression; sex steroid; pcos ... See more keywords