Steroidal alkaloids from the bulbs of Fritillaria pallidiflora Schrenk and their anti-inflammatory activity.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104845
Abstract: Steroidal alkaloids (1-11), including one new 24-hydroxylated cevanine-type steroidal alkaloid, named yibeinone F (1), were isolated from the bulbs of Fritillaria pallidiflora Schrenk. Their structures were elucidated by analyses of extensive spectroscopic data and comparison… read more here.
Keywords: anti inflammatory; fritillaria pallidiflora; bulbs fritillaria; pallidiflora schrenk ... See more keywords
Seasonal variation in toxic steroidal alkaloids of foothill death camas (Zigadenus paniculatus)
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Systematics and Ecology"
DOI: 10.1016/j.bse.2020.104044
Abstract: Abstract Death camas (Zigadenus spp.) is a common poisonous plant in North America with plants occurring in a wide variety of habitats with species of toxic concern occurring primarily in meadows, grasslands, shrublands, and mountains.… read more here.
Keywords: death camas; seed; steroidal alkaloids; plant ... See more keywords
Identification of candidate genes involved in steroidal alkaloids biosynthesis in organ-specific transcriptomes of Veratrum nigrum L.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.143962
Abstract: Veratrum nigrum is protected plant of Melanthiaceae family, able to synthetize unique steroidal alkaloids important for pharmacy. Transcriptomes from leaves, stems and rhizomes of in vitro maintained V. nigrum plants were sequenced and annotated for… read more here.
Keywords: alkaloids biosynthesis; steroidal alkaloids; identification candidate; veratrum nigrum ... See more keywords
Synthesis of C-Nor-D-homo-steroidal Alkaloids and Their Derivatives
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DOI: 10.1055/s-0036-1591965
Abstract: The C-nor-D-homo-steroidal alkaloid cyclopamine was discovered in the 1969 and in 2000 it was shown to act as an inhibitor of the hedgehog signaling (Hh) pathway, which is aberrantly activated in some tumors. Subsequently it… read more here.
Keywords: homo steroidal; homo; cyclopamine; synthesis homo ... See more keywords
Veratrum parviflorum poisoning: identification of steroidal alkaloids in patient blood and breast milk
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Toxicology"
DOI: 10.1080/15563650.2022.2132166
Abstract: Abstract Introduction The Veratrum genus is composed of plants containing a diverse set of steroidal alkaloids. Veratrum plant material has been utilized for centuries as herbal medicines, however the alkaloids have such a low therapeutic… read more here.
Keywords: veratrum; breast milk; parviflorum; steroidal alkaloids ... See more keywords
Steroidal alkaloids from the roots of Veratrum stenophyllum.
Sign Up to like & getrecommendations! Published in 2023 at "Fitoterapia"
DOI: 10.2139/ssrn.4314485
Abstract: Three new steroidal alkaloids, veratrasines A - C (1-3), along with ten known analogues (4-13) were isolated from the roots of Veratrum stenophyllum. Their structures were elucidated by NMR and HRESIMS data and comparison with the reported… read more here.
Keywords: roots veratrum; alkaloids roots; steroidal alkaloids; veratrum stenophyllum ... See more keywords
Potential of Steroidal Alkaloids in Cancer: Perspective Insight Into Structure–Activity Relationships
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.733369
Abstract: Steroidal alkaloids contain both steroidal and alkaloid properties in terms of chemical properties and pharmacological activities. Due to outstanding biological activities such as alkaloids and similar pharmacological effects to other steroids, steroidal alkaloids have received… read more here.
Keywords: activity relationships; activity; potential steroidal; structure activity ... See more keywords
Identification of Veratrum Species in Pimacao Based on ITS2 Sequences and Steroidal Alkaloids by a Pseudo-Targeted Metabolomics Method
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.831562
Abstract: Pimacao is a traditional Chinese folk medicine and is the main component of the famous Chinese herbal remedy “Yunnan Baiyao” for its significant analgesic activity in the treatment of wounds. Due to increases in consumption,… read more here.
Keywords: sequences steroidal; pseudo targeted; targeted metabolomics; its2 sequences ... See more keywords
Veratrum parviflorum: An Underexplored Source for Bioactive Steroidal Alkaloids
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27165349
Abstract: Plants of the Veratrum genus have been used throughout history for their emetic properties, rheumatism, and for the treatment of high blood pressure. However, inadvertent consumption of these plants, which resemble wild ramps, induces life-threatening… read more here.
Keywords: parviflorum; veratrum parviflorum; bioactive steroidal; parviflorum underexplored ... See more keywords
Potential Effect of Steroidal Alkaloids from Sarcococca saligna against Leishmania tropica
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.53.4s.161
Abstract: Background and Objectives: Sarcococca species have a rich source of steroidal alkaloids that possess different biological and pharmacological activities. Hence, present research was design to isolate the steroidal alkaloid from Sarcococca saligna and to evaluate… read more here.
Keywords: effect steroidal; compound holaphylline; potential effect; sarcococca saligna ... See more keywords