Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer
Sign Up to like & getrecommendations! Published in 2018 at "Steroids"
DOI: 10.1016/j.steroids.2018.02.003
Abstract: &NA; Steroidal derivatives have attracted tremendous attentions in biological and biomedical areas, due to their variety biological activities. The investigation of structural influences helps in understanding their biological activities. The interactions of steroidal derivatives with… read more here.
Keywords: quadruplex aptamer; steroidal derivatives; three steroidal; gggt quadruplex ... See more keywords
Investigations on 16-Arylideno Steroids as a New Class of Neuroprotective Agents for the Treatment of Alzheimer's and Parkinson's Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.6b00313
Abstract: Neuroinflammatory mechanisms mediated by activated glial and cytokines (TNF-α, IL-1β) might contribute to neuronal degeneration leading to Alzheimer's (AD) and Parkinson's disease (PD). Lipopolysaccharide (LPS) is an inflammogen derived from the cell wall of Gram-negative… read more here.
Keywords: steroidal derivatives; treatment; investigations arylideno; alzheimer parkinson ... See more keywords