Yeast-based evolutionary modeling of androgen receptor mutations and natural selection
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DOI: 10.1371/journal.pgen.1010518
Abstract: Cancer progression is associated with the evolutionary accumulation of genetic mutations that are biologically significant. Mutations of the androgen receptor (AR) are associated with the development of prostate cancer (PCa) by responding to non-androgenic hormones,… read more here.
Keywords: steroidal ligands; yeast based; androgen receptor; based evolutionary ... See more keywords