Steroidogenic potential of human fetal kidney at early gestational age
Sign Up to like & getrecommendations! Published in 2019 at "Steroids"
DOI: 10.1016/j.steroids.2019.05.009
Abstract: Steroidogenic potential of the human fetal kidney (hFK) at the end of first trimester is poorly investigated. Little is known about the ontogeny of steroidogenic enzymes and activities of steroidogenic pathways in the hFK at… read more here.
Keywords: steroidogenic potential; human fetal; fetal kidney; potential human ... See more keywords
P–664 Bone morphogenetic protein–7 (BMP–7) reduces E2 and P4 production of human luteinized granulosa cells by down-regulating the expression of the steroidogenic enzymes StAR and 3B-HSD
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.663
Abstract: What is the biological role of BMP–7 on the granulosa cells after luteinization? BMP–7 down regulates the steroidogenic enzymes and reduces E2 and P4 output of luteinized granulosa cells. BMP–7 is a member of TGF-B… read more here.
Keywords: granulosa cells; bmp; production; expression ... See more keywords
Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male rats
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Research"
DOI: 10.1093/toxres/tfac024
Abstract: Abstract Background Male reproductive damage is one of the most adverse side effects of doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable antioxidant potential. Objective The current research was designed to assess the… read more here.
Keywords: isorhamnetin flavonoid; dox; induced testicular; expression ... See more keywords
Local adrenomedullin gene delivery inhibits Leydig cell dysfunction by rescuing steroidogenic enzymes in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14545
Abstract: Adrenomedullin (ADM) has beneficial effects on Leydig cells under pathological conditions, including lipopolysaccharide (LPS)‐induced orchitis. Our previous studies demonstrated that ADM exerts a restorative effect on steroidogenesis in LPS‐treated primary rat Leydig cells by attenuating… read more here.
Keywords: cell dysfunction; leydig; leydig cell; rescuing steroidogenic ... See more keywords
Investigation of the effect of hesperidin on some reproductive parameters in testicular toxicity induced by Bisphenol A
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14562
Abstract: Bisphenol A (BPA) is one of the chemicals that cause dysfunction and infertility in testicles. Therefore, it is crucial to develop effective treatments against this damage. In this study, the effects of Hesperidin (HESP), a… read more here.
Keywords: inflammation; testicular toxicity; damage; toxicity induced ... See more keywords
Effect of cashew (Anacardium occidentale L.) nut-supplemented diet on steroidogenic enzymes, hormonal and oxidative imbalances, and sperm parameters in cisplatin-induced reproductive toxicity in male rats.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14100
Abstract: Cisplatin (CP) is a chemotherapeutic/anticancer drug culpable in sperm and testicular damage, but the use of dietary patterns has been reported to averse this effect. To date, no report on the use of roasted cashew… read more here.
Keywords: steroidogenic enzymes; toxicity; sperm parameters; nut supplemented ... See more keywords
Association of DNA methylation with steroidogenic enzymes in Cushing's adenoma.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine-related cancer"
DOI: 10.1530/erc-22-0115
Abstract: DNA methylation and demethylation regulate the transcription of genes. DNA methylation-associated gene expression of adrenal steroidogenic enzymes may regulate cortisol production in cortisol-producing adenoma (CPA). We aimed to determine the DNA methylation levels of all… read more here.
Keywords: methylation; dna methylation; cyp17a1 gene; steroidogenic enzymes ... See more keywords
Expression of steroidogenic enzymes in human placenta according to the gestational age.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular medicine reports"
DOI: 10.3892/mmr.2019.10048
Abstract: Female sex steroid hormones, including estradiol (E2) and progesterone (P4), serve significant physiological roles in pregnancy. In particular, E2 and P4 influence placenta formation, maintain pregnancy and stimulate milk production. These hormones are produced by… read more here.
Keywords: pregnancy; human placenta; expression; gestational age ... See more keywords