Perception, regulation, and fitness effects of pollen phytosterols in the bumble bee, Bombus terrestris.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of botany"
DOI: 10.1002/ajb2.16165
Abstract: PREMISE Many flowering plants depend on insects for pollination and thus attract pollinators by offering rewards, mostly nectar and pollen. Bee pollinators rely on pollen as their main nutrient source. Pollen provides all essential micro-… read more here.
Keywords: pollen; sterol; bee; fitness ... See more keywords
Mutations in the nucleotide‐binding domain of putative sterol importers Aus1 and Pdr11 selectively affect utilization of exogenous sterol species in yeast
Sign Up to like & getrecommendations! Published in 2019 at "Yeast"
DOI: 10.1002/yea.3456
Abstract: Sterol uptake in the yeast Saccharomyces cerevisiae is mediated by two plasma membrane ATP‐binding cassette transporters, Aus1 and Pdr11. Their expression is regulated by oxygen and is triggered by anaerobic growth conditions. Under these conditions,… read more here.
Keywords: utilization exogenous; exogenous sterol; yeast; sterol ... See more keywords
Sterol Evolution: Cholesterol Synthesis in Animals Is Less a Required Trait Than an Acquired Taste
Sign Up to like & getrecommendations! Published in 2020 at "Current Biology"
DOI: 10.1016/j.cub.2020.06.007
Abstract: Although cholesterol is considered a vital lipid for animals, not all animals can make cholesterol. A new study employing that celebrated elegant worm, Caenorhabditis elegans, investigates mechanisms that evolved in a sterol auxotroph to enable… read more here.
Keywords: cholesterol synthesis; cholesterol; sterol evolution; sterol ... See more keywords
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.04.044
Abstract: The azole antifungal drugs are an important class of chemotherapeutic agents with broad-spectrum of activity against yeasts and filamentous fungi, act in the ergosterol biosynthetic pathway through inhibition of the cytochrome P450-dependent enzyme sterol 14α-demethylase.… read more here.
Keywords: sterol demethylase; antileishmanial therapy; sterol; chemistry ... See more keywords
Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103089
Abstract: Summary Cellular cholesterol is regulated by at least two transcriptional mechanisms involving sterol-regulatory-element-binding proteins (SREBPs) and liver X receptors (LXRs). Although SREBP and LXR pathways are the predominant mechanisms that sense cholesterol in the endoplasmic… read more here.
Keywords: homeostasis; acid homeostasis; cholesterol; mice ... See more keywords
Safe intake of a plant sterol-enriched beverage with milk fat globule membrane: Bioaccessibility of sterol oxides during storage
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food Composition and Analysis"
DOI: 10.1016/j.jfca.2017.03.011
Abstract: Abstract Sterols in foods are susceptible to oxidation to form oxysterols. It is interesting for consumer health to know real intake and the possible associated adverse effects associated to oxysterols. This study measured oxysterol formation… read more here.
Keywords: storage; plant sterol; milk fat; beverage ... See more keywords
Sterol profile of Neobenedenia melleni, a marine ectoparasite fish.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2021.111414
Abstract: Neobenedenia melleni, a marine fish ectoparasite, is responsible for considerable losses in the mariculture industry. In maintaining the parasite's homeostasis, sterols are structural and functional lipids that perform vital functions. Thus, understanding the mechanisms of… read more here.
Keywords: neobenedenia melleni; melleni marine; sterol; profile neobenedenia ... See more keywords
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14711-4
Abstract: Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of functionally versatile proteins that play critical roles in the biogenesis, cellular localization and transport of RNA. Here, we outline a role for hnRNPs in gene regulatory circuits… read more here.
Keywords: metabolism mice; interactions heterogenous; sterol metabolism; sterol ... See more keywords
Crosstalk between protein N-glycosylation and lipid metabolism in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-51054-7
Abstract: The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation… read more here.
Keywords: protein glycosylation; sec59; glycosylation; crosstalk protein ... See more keywords
Down-regulation of tomato STEROL GLYCOSYLTRANSFERASE 1 perturbs plant development and facilitates viroid infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erac361
Abstract: Abstract Potato spindle tuber viroid (PSTVd) is a plant pathogen naturally infecting economically important crops such as tomato (Solanum lycopersicum). Here, we aimed to engineer tomato plants highly resistant to PSTVd and developed several S.… read more here.
Keywords: tomato sterol; sterol glycosyltransferase; pstvd; sterol ... See more keywords
The SMO1 Family of Sterol 4α-Methyl Oxidases Is Essential for Auxin- and Cytokinin-Regulated Embryogenesis1 [OPEN].
Sign Up to like & getrecommendations! Published in 2019 at "Plant physiology"
DOI: 10.1104/pp.19.00144
Abstract: In the plant sterol biosynthetic pathway, sterol 4α-methyl oxidase1 (SMO1) and SMO2 enzymes are involved in the removal of the first and second methyl groups at the C-4 position, respectively. SMO2s have been found to… read more here.
Keywords: auxin; smo1; auxin cytokinin; smo1 smo1 ... See more keywords