Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
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DOI: 10.1038/s41467-020-14711-4
Abstract: Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of functionally versatile proteins that play critical roles in the biogenesis, cellular localization and transport of RNA. Here, we outline a role for hnRNPs in gene regulatory circuits… read more here.
Keywords: metabolism mice; interactions heterogenous; sterol metabolism; sterol ... See more keywords
Spatial sterol metabolism unveiled by stimulated Raman imaging
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DOI: 10.3389/fchem.2023.1166313
Abstract: Spatiotemporal dynamics of small-molecule metabolites have gained increasing attention for their essential roles in deciphering the fundamental machinery of life. However, subcellular-level regulatory mechanisms remain less studied, particularly due to a lack of tools to… read more here.
Keywords: gem; sterol metabolism; sterol; spatial sterol ... See more keywords
The Effect of Orlistat on Sterol Metabolism in Obese Patients
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DOI: 10.3389/fendo.2022.824269
Abstract: Background Orlistat, a reversible inhibitor of pancreatic and gastric lipase, is known to have anti-obesity and antioxidant properties. Cholesterol intermediates and metabolites have diverse and important functions in cardiovascular disease. Therefore, we aimed to evaluate… read more here.
Keywords: group; effect orlistat; sterol metabolism; orlistat sterol ... See more keywords