Systemic Immunomodulating Therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis
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DOI: 10.1001/jamadermatol.2016.5668
Abstract: Importance Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are rare but severe adverse reactions with high mortality. There is no evidence-based treatment, but various systemic immunomodulating therapies are used. Objectives To provide an overview on… read more here.
Keywords: sjs ten; immunomodulating; analysis; systemic immunomodulating ... See more keywords
Prevalence of Leukopenia and Associated Outcomes in Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.3011
Abstract: This case series compares the factors, comorbidities, and complications associated with leukopenia between patients with and without leukopenia on hospital admission. read more here.
Keywords: outcomes patients; associated outcomes; prevalence leukopenia; patients stevens ... See more keywords
Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?
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DOI: 10.1001/jamaophthalmol.2017.0136
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous reactions affecting skin and mucous membranes.1 Affected patients usually develop a prodrome of fever and malaise, followed by the… read more here.
Keywords: sjs ten; genetics; johnson syndrome; sjs ... See more keywords
Syndrome de Stevens-Johnson-radiation recall secondaire au nivolumab
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DOI: 10.1016/j.annder.2017.09.027
Abstract: Introduction Le nivolumab est une immunotherapie utilisee dans le traitement du melanome metastatique et plus recemment dans celui du cancer bronchique non a petites cellules. Plusieurs cas de syndromes de Stevens-Johnson (SSJ) secondaires a ce… read more here.
Keywords: ssj; etait; radiation recall; stevens johnson ... See more keywords
Stevens-Johnson syndrome with vulvar involvement: A case report and literature review
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DOI: 10.1016/j.crwh.2022.e00404
Abstract: Stevens-Johnson syndrome is a rare, life-threatening mucocutaneous condition causing necrosis and detachment of the epidermis. Vulvovaginal involvement, seen in up to 70% of affected women, can lead to painful chronic conditions such as adenosis, hematocolpos,… read more here.
Keywords: involvement; case report; johnson syndrome; involvement case ... See more keywords
Stevens-Johnson syndrome and toxic epidermal necrolysis in pregnant patients: A systematic review
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DOI: 10.1016/j.ijwd.2020.04.002
Abstract: Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic emergencies. Although pregnant women comprise a subset of individuals at risk for SJS and TEN development, little is known… read more here.
Keywords: epidermal necrolysis; pregnant patients; toxic epidermal; stevens johnson ... See more keywords
Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults.
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DOI: 10.1016/j.jaad.2020.02.066
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists,… read more here.
Keywords: dermatology; supportive care; johnson syndrome; management ... See more keywords
Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immunocell activation
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DOI: 10.1016/j.jaad.2020.06.043
Abstract: Abstract Background Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied. Objective To summarize clinical characteristics of SJS/TEN-associated acute pancreatic… read more here.
Keywords: sjs ten; pancreatic injuries; johnson syndrome; epidermal necrolysis ... See more keywords
Performance of ABCD-10 and SCORTEN Mortality Prediction Models in a Cohort of Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.
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DOI: 10.1016/j.jaad.2021.04.082
Abstract: BACKGROUND ABCD-10 has recently been proposed as an alternative to the SCORTEN model for predicting in-hospital mortality in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. In contrast to SCORTEN, ABCD-10 incorporates prior dialysis and… read more here.
Keywords: abcd; johnson syndrome; mortality; syndrome toxic ... See more keywords
Inhibition of tumor necrosis factor improves conventional steroid therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis.
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DOI: 10.1016/j.jaad.2022.01.039
Abstract: BACKGROUND Systemic steroid therapies for Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have been challenged due to their limited benefits. Whether additional tumor necrosis factor (TNF)-α inhibition provides an optimized approach remains unexplored. OBJECTIVE To investigate… read more here.
Keywords: epidermal necrolysis; johnson syndrome; inhibition; therapy ... See more keywords
Tenofovir-induced Stevens-Johnson syndrome in a patient with acute hepatitis B: A rare case report.
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DOI: 10.1016/j.japh.2020.06.029
Abstract: OBJECTIVE To report a rare case of a hepatitis B patient who developed the Stevens-Johnson syndrome (SJS) secondary to tenofovir use. CASE SUMMARY A 61-year-old woman presented with complaints of jaundice, difficulty in swallowing, and… read more here.
Keywords: rare case; tenofovir; johnson syndrome; case ... See more keywords