Small CAG Repeat RNA Forms a Duplex Structure with Sticky Ends That Promote RNA Condensation.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c16886
Abstract: Biomolecular condensation lays the foundation of forming biologically important membraneless organelles, but abnormal condensation processes are often associated with human diseases. Ribonucleic acid (RNA) plays a critical role in the formation of biomolecular condensates by… read more here.
Keywords: small cag; sticky ends; condensation; cag repeat ... See more keywords
Control and synchronization of rapid nanoscale DNA heat engine by local heating
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adx6316
Abstract: To further activate devices based on DNA nanotechnology, we introduce an approach that notably enhances both the speed and force of DNA powered machines and artificial hinge machine. A microheater, with millisecond response, heats or… read more here.
Keywords: sticky ends; synchronization rapid; dna origami; machine ... See more keywords
Understanding the self-assembly dynamics of A/T absent ‘four-way DNA junctions with sticky ends’ at altered physiological conditions through molecular dynamics simulations
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0278755
Abstract: Elucidation of structure and dynamics of alternative higher-order structures of DNA such as in branched form could be targeted for therapeutics designing. Herein, we are reporting the intrinsically dynamic and folds transitions of an unusual… read more here.
Keywords: dna; four way; sticky ends; way dna ... See more keywords