Collagen Stiffness and Architecture Regulate Fibrotic Gene Expression in Engineered Adipose Tissue
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DOI: 10.1002/adbi.201900286
Abstract: Adipose tissue (AT) has a dynamic extracellular matrix (ECM) surrounding adipocytes that allows for remodeling during metabolic fluctuations. During the progression of obesity, AT has increased ECM deposition, stiffening, and remodeling, resulting in a pro‐fibrotic… read more here.
Keywords: collagen; stiffness architecture; expression; gene expression ... See more keywords