The stiffness-dependent tumor cell internalization of liquid metal nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr04293b
Abstract: The properties of nanoparticle (NP) carriers, such as size, shape and surface state, have been proven to dramatically affect their uptake by tumor cells, thereby influencing and determining the effect of nanomedicine on tumor theranostics.… read more here.
Keywords: liquid metal; tumor; internalization; stiffness dependent ... See more keywords
Signaling Downstream of Focal Adhesions Regulates Stiffness-Dependent Differences in the TGF-β1-Mediated Myofibroblast Differentiation of Corneal Keratocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.886759
Abstract: Following injury and refractive surgery, corneal wound healing can initiate a protracted fibrotic response that interferes with ocular function. This fibrosis is related, in part, to the myofibroblast differentiation of corneal keratocytes in response to… read more here.
Keywords: myofibroblast differentiation; corneal keratocytes; differentiation; differentiation corneal ... See more keywords
Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
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DOI: 10.3389/fonc.2018.00337
Abstract: The persistence of drug resistant cell populations following chemotherapeutic treatment is a significant challenge in the clinical management of cancer. Resistant subpopulations arise via both cell intrinsic and extrinsic mechanisms. Extrinsic factors in the microenvironment,… read more here.
Keywords: breast; response; matrix; cancer ... See more keywords
Identification of Prognostic Genes in Gliomas Based on Increased Microenvironment Stiffness
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DOI: 10.3390/cancers14153659
Abstract: Simple Summary Glioblastoma multiforme (GBM) is the most aggressive primary brain cancer; less than 50% of patients with GBM survive longer than 15 months. A biomarker for early GBM diagnosis can substantially increase the effectiveness… read more here.
Keywords: prognosis; prognostic genes; stiffness; glioma ... See more keywords