Anti-nociceptive effect of stigmasterol in mouse models of acute and chronic pain
Sign Up to like & getrecommendations! Published in 2017 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-017-1416-x
Abstract: Stigmasterol is a common sterol found in plants, but the anti-nociceptive effect of this compound and its mechanism of action are not fully explored. Thus, in the present study, the anti-nociceptive effect of stigmasterol was… read more here.
Keywords: effect stigmasterol; stigmasterol; anti nociceptive; nociceptive effect ... See more keywords
Thermal degradation of stigmasterol under the deodorisation temperature exposure alone and in edible corn oil.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.131030
Abstract: Phytosterols are commonly found in vegetable oils and possess health benefits for humans. While investigating the chemical conversion of stigmasterol at deodorisation temperatures, gas chromatography-mass spectrometry (GC-MS) and ultra-high performance liquid chromatography coupled to high-resolution… read more here.
Keywords: stigmasterol; deodorisation; degradation; corn oil ... See more keywords
Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10209-0
Abstract: Type 2 diabetes results from defects in both insulin sensitivity and insulin secretion. Elevated cholesterol content within pancreatic β-cells has been shown to reduce β-cell function and increase β-cell apoptosis. Hyperglycemia and dyslipidemia contribute to… read more here.
Keywords: glucolipotoxicity; insulin secretion; cholesterol; stigmasterol ... See more keywords
Self-assembly of naturally occurring stigmasterol in liquids yielding a fibrillar network and gel
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/c9ra10376g
Abstract: Stigmasterol, a naturally occurring 6-6-6-5 monohydroxy phytosterol, was extracted from the leaves of Indian medicinal plant Roscoea purpurea, commonly known as Kakoli. In continuation of our studies on the self-assembly properties of naturally occurring terpenoids,… read more here.
Keywords: liquids yielding; self assembly; microscopy; fibrillar network ... See more keywords
The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Disease Markers"
DOI: 10.1155/2021/4304507
Abstract: Purpose This study was aimed at exploring the regulatory mechanism of Xiaoyao San (XYS) and its main compound, Stigmasterol, in the biological network and signaling pathway of ovarian cancer (OC) through network pharmacology-based analyses and… read more here.
Keywords: network; treatment; pi3k akt; stigmasterol ... See more keywords
Determination of stigmasterol hydroperoxides using high-performance liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization
Sign Up to like & getrecommendations! Published in 2018 at "Czech Journal of Food Sciences"
DOI: 10.17221/10639-cjfs
Abstract: A new specific method using high-performance liquid chromatography-mass spectrometry (HPLC-MS) for the detection of stigmasterol hydroperoxides was developed. Hydroperoxides of stigmasterol were obtained by photo-oxidation (90 min) in the presence of methylene blue as a… read more here.
Keywords: mass; stigmasterol; performance liquid; using high ... See more keywords
Tomato Sterol 22-desaturase Gene CYP710A11: Its Roles in Meloidogyne incognita Infection and Plant Stigmasterol Alteration
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315111
Abstract: Sterols are isoprenoid-derived lipids that play essential structural and functional roles in eukaryotic cells. Plants produce a complex mixture of sterols, and changes in plant sterol profiles have been linked to plant–pathogen interactions. β-Sitosterol and… read more here.
Keywords: sterol desaturase; cyp710a11; stigmasterol; plant ... See more keywords
Stigmasterol Causes Ovarian Cancer Cell Apoptosis by Inducing Endoplasmic Reticulum and Mitochondrial Dysfunction
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12060488
Abstract: Background: Phytosterols have physiological effects and are used as medicines or food supplements. Stigmasterol has shown anticancer effects against various cancers such as hepatoma, cholangiocarcinoma, gall bladder carcinoma, endometrial adenocarcinoma and skin, gastric, breast, prostate,… read more here.
Keywords: cancer cells; stigmasterol; ovarian cancer; cancer cell ... See more keywords