Usefulness of imaging findings in predicting tumor-infiltrating lymphocytes in patients with breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "European Radiology"
DOI: 10.1007/s00330-019-06516-x
Abstract: Objectives Tumor-infiltrating lymphocytes (TILs) have been determined as a new prognostic indicator of immunotherapy response in breast cancer (BC). The aim of this study is to investigate the effectiveness of imaging features in predicting the… read more here.
Keywords: stil levels; infiltrating lymphocytes; imaging findings; stil ... See more keywords
Bimodal Binding of STIL to Plk4 Controls Proper Centriole Copy Number.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.030
Abstract: The number of centrioles is tightly controlled to ensure bipolar spindle assembly, which is a prerequisite to maintain genome integrity. However, our understanding of the fundamental principle that governs the formation of a single procentriole… read more here.
Keywords: plk4; bimodal binding; stil; formation ... See more keywords
The human oncogene SCL/TAL1 interrupting locus (STIL) promotes tumor growth through MAPK/ERK, PI3K/Akt and AMPK pathways in prostate cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.11.048
Abstract: The morbidity and mortality of prostate cancer (PCa) in China have increased obviously, which became the second leading cause of death in men with cancer. Hedgehog (Hh) signaling pathway is a key signaling pathway involved… read more here.
Keywords: stil; prostate cancer; signaling pathway; human oncogene ... See more keywords
STIL Acts as an Oncogenetic Driver in a Primary Cilia-Dependent Manner in Human Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.804419
Abstract: SCL/TAL1 Interrupting locus (STIL) is a ciliary-related gene involved in regulating the cell cycle and duplication of centrioles in dividing cells. STIL has been found disordered in multiple cancers and driven carcinogenesis. However, the molecular… read more here.
Keywords: cell cycle; expression; stil; cancer ... See more keywords
STIL Endows Oncogenic and Stem-Like Attributes to Colorectal Cancer Plausibly by Shh and Wnt Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.581671
Abstract: The discovery of a potent gene regulating tumorigenesis and drug resistance is of high clinical importance. STIL is an oncogene; however, its molecular associations and role in colorectal oncogenesis are unknown. In this study, we… read more here.
Keywords: stil endows; stil; colorectal cancer; crc ... See more keywords